Synthesis of new C3 symmetric amino acid- and aminoalcohol-containing chiral stationary phases and application to HPLC enantioseparations was written by Yu, Jeongjae;Armstrong, Daniel W.;Ryoo, Jae Jeong. And the article was included in Chirality in 2018.Computed Properties of C10H11NS2 This article mentions the following:
We recently reported a new C3-sym. (R)-phenylglycinol N-1,3,5-benzenetricarboxylic acid-derived chiral high-performance liquid chromatog. (HPLC) stationary phase (CSP 1) that demonstrated better results as compared to a previously described N-3,5-dintrobenzoyl (DNB) (R)-phenylglycinol-derived CSP. Over a decade ago, (S)-leucinol, (R)-phenylglycine, and (S)-leucine derivatives were used as the starting materials of 3,5-DNB-based Pirkle-type CSPs for chiral separation In this study, three new C3-sym. CSPs (CSP 2, 3, and 4) were prepared by combining the ideas and results mentioned above. Here we describe the synthetic procedures and applications of the new C3-sym. CSPs (CSP 2-CSP 4). In the experiment, the researchers used many compounds, for example, (R)-4-Benzylthiazolidine-2-thione (cas: 110199-17-2Computed Properties of C10H11NS2).
(R)-4-Benzylthiazolidine-2-thione (cas: 110199-17-2) belongs to thiazolidine derivatives. Thiazolidine derivatives have been found to exhibit very prominent anti-inflammatory and anti-nociceptive activity. Thiazolidines have been applied as prodrug derivatives for various steroids containing a 3-carbonyl group to improve their topical anti-inflammatory activity. Computed Properties of C10H11NS2
Referemce:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com