New discoveries in chemical research and development in 2021. The appropriate choice of redox mediator can avoid electrode passivation and overpotential, which strongly inhibit the efficient activation of substrates in electrolysis. In a patent, 2682-49-7, name is Thiazolidin-2-one, introducing its new discovery. Reference of 2682-49-7
Thiazolidinone and its derivatives have high pharmacological relevance since they are available in both natural products and Pharmaceutical compounds. The main synthetic routes to thiazolidinones comprising three components such as an amine, a carbonyl group and mercapto acid. The classical method of synthesis reported may be either a one-pot three-component condensation method or a two-step process. Synthesis and anticancer activity evaluation of thiazolidinones containing benzothiazole moiety. These compounds were screened for in-vitro anticancer activity. The activity data exhibits that all compounds were found to show potent anticancer activity. Various substituents at C-2 and C-3 of thiazolidinone results in potent anticancer activity. Prompted by these reports, we aimed to prepare the following series of 2, 3-disubstituted-Thiazolidinone derivatives as potent anticancer agents.
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Reference：
Quinuclidine – Wikipedia,
Quinuclidine | C7H414N | ChemSpider