Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Comparative Study, Article, Hoppe-Seyler’s Zeitschrift fuer Physiologische Chemie called The metabolism of tryptophan and 7-chlorotryptophan in Pseudomonas pyrrocinia and Pseudomonas aureofaciens, Author is Luebbe, Claus; Van Pee, Karl Heinz; Salcher, Olga; Lingens, Franz, which mentions a compound: 63352-97-6, SMILESS is O=C(O)CC1=CNC2=C1C=CC=C2Br, Molecular C10H8BrNO2, HPLC of Formula: 63352-97-6.
P. pyrrocinia ATCC 15958 and a mutant strain (ACN) of P. aureofaciens ATCC 15926 possess a mechanism for the degradation of the tryptophan side chain. Indole, indole-3-carboxylic acid, indole-3-acetic acid, the corresponding compounds chlorinated or brominated at position 7, indole-3-pyruvate, and 7-chloroindole-3-pyruvate were isolated from bacterial cultures. The chlorinated indole derivatives were isolated after the addition of 7-chloro-DL-tryptophan to cultures of P. pyrrocinia whereas their bromo analogs were found in the culture medium of the mutant strain ACN of P. aureofaciens, grown in the presence of NaBr. Enzymic studies show that tryptophan is transaminated to indole-3-pyruvate, which is transformed to indole-3-acetaldehyde. Dehydrogenation of indole-3-acetaldehyde leads to indole-3-acetic acid, which is further metabolized to indole-3-carboxaldehyde and converted by dehydrogenation to indole-3-carboxylic acid. Indole is formed by the spontaneous decarboxylation of indole-3-carboxylic acid.
In addition to the literature in the link below, there is a lot of literature about this compound(2-(7-Bromo-1H-indol-3-yl)acetic acid)HPLC of Formula: 63352-97-6, illustrating the importance and wide applicability of this compound(63352-97-6).
Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com