Recommanded Product: 94-41-7. In 2020.0 J FOOD SCI published article about RADICAL-SCAVENGING ACTIVITY; CHEMICAL-COMPOSITION; ANTIOXIDANT ACTIVITY; SAN-JUAN; CHALCONES; PUNCTATA; EXTRACTS; REGIONS; ANTIBACTERIAL; MANAGEMENT in [Salas, Ana L.; Orqueda, Maria Eugenia; Uriburu, Florencia M. Correa; Perez, Maria Jorgelina; Alvarez, Maria de los Angeles; Zampini, Iris Catiana; Isla, Maria Ines] CONICET UNT, Inst Bioprospecc & Fisiol Vegetal INBIOFIV, RA-4000 San Miguel De Tucuman, Tucuman, Argentina; [Salas, Ana L.; Uriburu, Florencia M. Correa; Zampini, Iris Catiana; Isla, Maria Ines] Univ Nacl Tucuman, Fac Ciencias Nat, RA-4000 San Miguel De Tucuman, Tucuman, Argentina; [Mercado, Maria Ines; Garcia, Maria Elena; Ponessa, Graciela I.; Zampini, Iris Catiana; Isla, Maria Ines] Fdn Miguel Lillo, Area Bot, Inst Morfol Vegetal, RA-4000 San Miguel De Tucuman, Tucuman, Argentina; [Uriburu, Florencia M. Correa; Maldonado, Luis Maldonado] Inst Nacl Tecnol Agr INTA, Estn Expt Agr Famailla, RA-4132 Famailla, Tucuman, Argentina in 2020.0, Cited 48.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.
The effect of Argentine propolis extracts against enzymes related to metabolic syndrome and oxidative stress, as well as the botanical origin of raw propolis, were studied. Histological and chemical analyses of propolis samples revealed that the botanical origin isZuccagnia punctata, an Argentine medicinal plant. The melissopalynological analysis showed both pollen grains ofZ. punctataand the other plant species. This result indicates that the differences found in the botanical remains compared to the palynological studies may have been caused by the bees selecting resinous shrubs mainly ofZ. punctatafor the production of propolis and other plants with flowers for the production of honey. The richness of propolis was remarkable in two flavonoid precursors (2 ‘,4 ‘-dihydroxy-3 ‘-methoxychalcone, 2 ‘,4 ‘-dihydroxychalcone), the major chemical components ofZ. punctata. The hydroalcoholic extracts of Argentine propolis andZ. punctatawere able to inhibit enzymes associated with the metabolic syndrome, including alpha-glucosidase, alpha-amylase and lipase, with IC(50)values between 7 to 14, 37 to 48, and 13 to 28 mu g/mL, respectively. Biological activity was mainly attributed to chalcones. Oxygen and nitrogen reactive species scavenging activity was determined by the assays of superoxide radical (O-2(center dot-)), hydroxyl radical (HO center dot), hydrogen peroxide (H2O2), nitric oxide (NO center dot), and cation radical (ABTS(center dot+)). Results showed SC(50)values between 115 to 278, 12.50 to 46; 39 to 92; 50 to 104.50 and 23 to 33.75 mu g/mL, respectively. This study suggests for the first time that propolis from Argentina is highly effective in inhibiting enzymes related to the metabolic syndrome and in free-radical scavenging that would justify its use as a dietary supplement or as a functional ingredient in special food. Practical Application Propolis from Catamarca, Argentina, is traditionally used as medicine and food. Its botanical origin isZuccagnia punctata, an endemic plant species popularly used as a medicine in Argentina. Propolis has the ability to regulate the activity of enzymes involved in the carbohydrate and lipid metabolism, and consequently in metabolic syndrome. Besides, its antioxidant capacity makes it a natural product that can be used as a dietary supplement or as a functional ingredient in special foods. It is important to highlight that in the Argentine Food Code, propolis was incorporated in 2008 as a dietary supplement and the present results give major added value to this product.
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Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com