Vichard, Dominique; Gruselle, Michel; Jaouen, Gerard; Nefedova, Marina N.; Mamedyarova, Irina A.; Sokolov, Viatcheslav I.; Vaissermann, Jacqueline published the article 《Synthesis, X-ray structure and chemical properties of 17α-ferrocenylestradiol》. Keywords: ferrocenylestradiol crystal structure reaction; estradiol ferrocenyl crystal structure reaction.They researched the compound: Bromoferrocene( cas:1273-73-0 ).Safety of Bromoferrocene. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:1273-73-0) here.
The X-ray structure of 17α-ferrocenylestradiol shows that the ferrocenyl group is at the α-position of the steroid, below the plane of the D ring. From acidic medium it is possible to obtain and isolate the derivative with a carbenium ion in 17-α position. This ion is transformed by various nucleophiles into the C(16)-C(17)-unsaturated derivative With NaBH4 in acidic medium the reduction leads to a mixture of 17α- and 17β-ferrocenylestrol with a predominance of the β product, owing to a more favorable entrance of hydride in the α position. The oxidized derivative 17α-ferrociniumylestradiol tetrafluoroborate was prepared and its properties are described.
This literature about this compound(1273-73-0)Safety of Bromoferrocenehas given us a lot of inspiration, and I hope that the research on this compound(Bromoferrocene) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com