Recommanded Product: Chalcone. I found the field of Chemistry very interesting. Saw the article Catalytic Asymmetric Three-component Hydroacyloxylation/ 1,4-Conjugate Addition of Ynamides published in 2020, Reprint Addresses Cao, WD; Feng, XM (corresponding author), Sichuan Univ, Coll Chem, Key Lab Green Chem & Technol, Minist Educ, Chengdu 610064, Peoples R China.. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone.
A highly enantioselective three-component hydroacyloxylation/1,4-conjugate addition ofortho-hydroxybenzyl alcohols, ynamides and carboxylic acids was developed under mild reaction conditions in the presence of a chiralN,N ‘-dioxide/Sc(OTf)(3)complex, which went throughin situgeneratedortho-quinone methides with alpha-acyloxyenamides, delivering a range of corresponding chiral alpha-acyloxyenamides derivatives containinggem(1,1)-diaryl skeletons in moderate to good yields with excellenteevalues. The scale-up experiment and further derivation showed the practicality of this catalytic system. In addition, a possible catalytic cycle and transition state model was proposed to elucidate the origin of the stereoselectivity based on X-ray crystal structure of the alpha-acyloxyenamide intermediate and product.
Recommanded Product: Chalcone. Bye, fridends, I hope you can learn more about C15H12O, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com