In an article, author is Mushtaque, Md, once mentioned the application of 2421-28-5, Category: thiazolidines, Name is Benzophenone-3,3′,4,4′-tetracarboxylic dianhydride, molecular formula is C17H6O7, molecular weight is 322.23, MDL number is MFCD00005923, category is thiazolidines. Now introduce a scientific discovery about this category.
Experimental and theoretical studies of a pyrazole-thiazolidin-2,4-di-one hybrid
The present work describes synthesis, characterization and biological evaluations of a hybrid compound 10 composed of two intriguing scaffolds pyrazole and thiazolidin-2,4-di-one. The title compound was obtained via multi-step reaction and characterized by a number of techniques (viz. IR, UV Visible, H-1-NMR, C-13-NMR and MS) including X-ray crystallography. The structural and photophysical data of compound 10 were well supported by theoretical calculations performed at density functional (DFT) level. In-vitro anticancer studies on different human cancer cell lines indicated moderate to low activity of the compounds. The molecular target of the compound was predicted through in-silico studies. Finding of the studies are presented herein. (C) 2017 Elsevier B.V. All rights reserved.
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Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com