In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Reactions on solid supports. Part-3. Hydrogen isotope exchange reactions catalyzed by montmorillonite clay, published in 1989-10-31, which mentions a compound: 2199-44-2, mainly applied to isotope exchange deuterated clay organic; montmorillonite clay isotope exchange catalysis, Recommanded Product: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate.
Deuterated clay in which the interlammelar water has been replaced by deuterium oxide can be used for exchange of acidic protons in a variety of organic substrates. β-Keto esters and β-diketones undergo rapid exchange of the methylene protons in chloroform solutions in presence of deuterated clay; pyrrole undergoes exchange of all protons, whereas indoles preferentially undergo exchange at the 3-position as expected, although prolonged exposure to the reagent leads to exchange at other positions.
After consulting a lot of data, we found that this compound(2199-44-2)Recommanded Product: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com