Recommanded Product: Chalcone. I found the field of Chemistry very interesting. Saw the article Asymmetric epoxidation of alpha,beta-unsaturated ketones catalyzed by rare-earth metal amides RE[N(SiMe3)(2)](3) with chiral TADDOL ligands published in 2021.0, Reprint Addresses Lu, CR; Zhao, B (corresponding author), Soochow Univ, Key Lab Organ Synth Jiangsu Prov, Coll Chem Chem Engn & Mat Sci, Suzhou 215123, Peoples R China.. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone.
The catalytic asymmetric epoxidation of alpha,beta-unsaturated ketones by tert-butylhydroperoxide (TBHP) has been well established using rare-earth metal amides RE[N(SiMe3)(2)](3) (RE = La(1), Nd(2), Sm(3), Y(4), Yb(5)) with chiral TADDOL ligands. It was found that the combination of Yb[N(SiMe3)(2)](3) and chiral TADDOL ligand H2L2 ((4S,5S)-2,2-dimethyl-alpha,alpha,alpha ‘,alpha ‘-tetra-3,5-bis(trifluormethylphenyl)-1,3-dioxolane-4,5-dimethanol) in a 1 : 1 molar ratio was the optimal choice, which provided the desired epoxides in excellent yields (89-99%) and good to high enantioselectivities (57-94% ee), using DBU as an additive. Various substrates were proved to have functional group tolerance. In addition, gram-level experiments and derivatization experiments were also studied.
Recommanded Product: Chalcone. Welcome to talk about 94-41-7, If you have any questions, you can contact Shan, HW; Lu, CR; Zhao, B; Yao, YM or send Email.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com