A balanced equation for a chemical reaction indicates what is reacting and what is produced, but it reveals nothing about how the reaction actually takes place. The reaction mechanism is the process, or pathway, by which a reaction occurs.26364-65-8, name is 2-Cyanoimino-1,3-thiazolidine. An updated downstream synthesis route of 26364-65-8 as follows., 26364-65-8
N-t-Butyloxycarbonylglutamine (2.0 g, 8.12 mmol) was dissolved in THF (5 mL) and cooled TO-15C. CAIBE (ISOBUTYLCHLOROFORMATE) (1.06 mL, 8.12 mmol) and 4- METHYLMORPHOLINE (0.895 mL, 8.12 mmol) were added and the solution stirred for 15 min, The formation of the mixed anhydride was checked by TLC (eluent: CHCL3/MEOH : 9/1). After warming to-10C another equivalent of 4-methylmorpholine (0.895 mL, 8.12 mmol) and THIAZOLIDINEHYDROCHLORIDE (1.02 g, 8. 12 mmol) was added. The mixture was brought to room temperature and stirred overnight. The sediment FORMED was filtered off and the solvent was evaporated. The resulting oil was taken up in chloroform (20 ml) and washed with a saturated solution of sodium hydrogensulfate followed by a saturated solution of sodium bicarbonate, water and brine. The organic layer was separated, dried and evaporated. The resulting product was checked for purity by TLC (eluent: CHC13/MEOH : 9/1). Yield: 1.64 g. A portion of this product (640 mg) was dissolved in 3.1 mL ice cold HCl in dioxane (12.98 M, 20 equivalents) and left on ice. The progress of the reaction was monitored by TLC (eluent: CHCL3/MEOH : 9/1). After completion of the reaction the solvent was removed and the resulting residue was taken up in methanol and evaporated again. The resulting oil was dried over phosphorous-V-oxide and triturated twice with diethylether to give the title compound (0.265 g). The purity was checked by HPLC. The identity of the reaction product was checked by NMR analysis.
There are, however, a few established termolecular elementary reactions. The reaction of nitric oxide with oxygen appears to involve termolecular steps. you can also browse my other articles about Thiazolidine hydrochloride
Reference£º
Patent; PROSIDION LTD.; WO2005/20983; (2005); A2;,
Thiazolidine – Wikipedia
Thiazolidine – ScienceDirect.com