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Synthesis of bis-dibenzonaphthyridines and evaluation of their antibacterial activity
Reaction of phthalic acid with 2-methyl-4-N-phenylaminoquinoline under PPA condition resulted in the formation of 6-methyldibenzo[b, h][1,6]naphthyridines, whereas the same reaction with 2,4-bis(N-phenylamino)quinoline resulted in the dimeric dibenzo[b, h][1,6]naphthyridines. A novel mechanism has been proposed to explain the formation of the unexpected product. Screening for the antibacterial activity against various pathogens, proved that the dimeric analogs showed a better antibacterial activity when compared to their monomeric analogs.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Reference of 1055361-35-7, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about Reference of 1055361-35-7
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Quinuclidine – Wikipedia,
Quinuclidine | C7H933N | ChemSpider