The Best Chemistry compound: 2199-44-2

Compound(2199-44-2)Product Details of 2199-44-2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate), if you are interested, you can check out my other related articles.

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate( cas:2199-44-2 ) is researched.Product Details of 2199-44-2.Sundukova, T. A.; Vasilevskii, S. F.; Shvartsberg, M. S.; Kotlyarevskii, I. L. published the article 《Acetylene condensation in a series of pyrroles》 about this compound( cas:2199-44-2 ) in Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya. Keywords: acetylene condensation pyrrolecarboxylate. Let’s learn more about this compound (cas:2199-44-2).

Condensation of Et 4-iodo-3,5-dimethylpyrrole-2-carboxylate with HCCR(R = Ph, morpholinomethyl) in Et2NH in the presence of Pd (PPh3)2Cl2 and CuI gave ethynylpyrroles I in 64 and 68% yield, resp. Similar reaction with HOCMe2CCH gave the deiodinated product in 18% yield. Treatment of II (R = I) with CuCCPh in pyridine-DMF at reflux gave 78.0% II (R = CCPh). Deiodination of III (R = I) (IV) was easier than with the 4-iodo-2-carboxylate derivative but more difficult than II (R = I). In the presence of Pd complex catalyst condensation of IV and PhCCH gave concurrent redn and substitution.

Compound(2199-44-2)Product Details of 2199-44-2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate), if you are interested, you can check out my other related articles.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com