Application In Synthesis of Chalcone. I found the field of Chemistry very interesting. Saw the article Synthesis of Trifluoromethyl- and Ester Group-Substituted alpha-Carbolines via Iron-Catalyzed Tandem Cyclization Reaction published in 2020.0, Reprint Addresses Wan, CF; Liu, JB (corresponding author), Jiangxi Normal Univ, Coll Chem & Chem Engn, Minist Educ, Nanchang 330022, Jiangxi, Peoples R China.; Wan, CF; Liu, JB (corresponding author), Jiangxi Normal Univ, Key Lab Funct Small Organ Mol, Minist Educ, Nanchang 330022, Jiangxi, Peoples R China.; Liu, JB (corresponding author), Jiangxi Univ Sci & Technol, Sch Met & Chem Engn, Ganzhou 341000, Peoples R China.. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone.
An efficient approach to prepare trifluoromethyl-alpha-carbolines and ester group-substituted alpha-carbolines via the tandem cyclization reaction of 2-(2-aminophenyl)acetonitriles and trifluoromethyl 1,3-diones or beta,gamma-unsaturated alpha-ketoesters was reported. The transformation proceeded smoothly in the presence of catalytic environmental-benign iron salts, which are used to prepare the desired products in moderate to good yields.
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Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com