Healthcare careers for chemists are once again largely based in laboratories, although increasingly there is opportunity to work at the point of care, helping with patient investigation. In a patent, 76186-04-4, name is (S)-4-Isopropylthiazolidine-2-thione, introducing its new discovery. Formula: C6H11NS2
A total synthesis of the proposed structure of the natural macrolactone phomolide G (1) by a bidirectional strategy from L-tartaric acid is reported. The omega-terminus of the molecule was elaborated by nitrile extension, C3-alkylation and a substrate-controlled 1,3-ketone reduction. The alpha-terminus was extended by a C2aldehyde-to-alkenal homologation followed by an auxiliary controlled aldol reaction. Macrolactonization and deprotection yielded compound 1 (confirmed by X-ray analysis). This putative structure of phomolide G displayed discordant NMR spectroscopic data in comparison with those of the natural product. Detailed inspection of all NMR spectroscopic data available indicated phomolide G to be likely a diastereomer of 1. The synthetic strategy developed allows control of the absolute stereochemistry at all four chiral secondary alcohol groups. Further manipulation allowed for the preparation of diastereomer 33, the1H and13C NMR spectroscopic data of which are in full accord with that reported for the natural product.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Formula: C6H11NS2, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about Formula: C6H11NS2
Reference：
Quinuclidine – Wikipedia,
Quinuclidine | C7H738N | ChemSpider