New Advances in Chemical Research, May 2021. HPLC of Formula: C19H11F3N2O4S, Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. In a document type is Article, and a compound is mentioned, 1055361-35-7, 4-(4-((2,4-Dioxothiazolidin-5-ylidene)methyl)-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrile, introducing its new discovery.
A series of novel 4-anilinoquinoline derivatives were synthesized and evaluated for their antiproliferative activities. Among them, 14h exhibited the most potent cytotoxic activity with IC50 values ranging from 1.5 to 3.9 nM against all tested cancer cell lines, and showed promising efficacy in multidrug resistant cancer cells. Flow cytometry assay, immune-fluorescence staining, microtubule dynamics assays and competition assays with EBI identified that 14h was a novel tubulin depolymerization agent by binding to the colchicine site. Importantly, in vivo efficacy evaluation of HCT116 xenograft model, 14h showed efficient antitumor activity without significant loss in body weight. All the results indicated that 14h could be a promising candidate for the treatment of cancer.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, HPLC of Formula: C19H11F3N2O4S, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about HPLC of Formula: C19H11F3N2O4S
Reference：
Quinuclidine – Wikipedia,
Quinuclidine | C7H950N | ChemSpider