Tag: M.W=200-250

Recently I am researching about BACTERIAL LEAF-BLIGHT; ORYZAE PV. ORYZAE; ANTIBACTERIAL ACTIVITY; ANTIVIRAL ACTIVITY; MOLECULAR DOCKING; RESISTANCE GENES; DESIGN; ANTICANCER; HYBRIDS; CYTOTOXICITY, Saw an article supported by the National Key Research and Development Program of China [2017YFD0200506]; Science and Technology Project of Guizhou Province [20185781]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Guo, T; Xia, ROJ; Chen, M; He, J; Su, SJ; Liu, LW; Li, XY; Xue, W. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone. Safety of Chalcone

A series of novel chalcone derivatives containing a thiophene sulfonate group were designed and synthesized. The structures of all title compounds were determined by H-1-NMR, C-13-NMR and HRMS. Antibacterial bioassays indicated that, compound 2l demonstrated excellent antibacterial activities against Xanthomonas axonopodis pv. citri (Xac), with an EC50 value of 11.4 mu g mL(-1), which is significantly superior to those of bismerthiazol (BT) (51.6 mu g mL(-1)) and thiodiazole-copper (TC) (94.7 mu g mL(-1)). Meanwhile, the mechanism of action of compound 2l was confirmed by using scanning electron microscopy (SEM). In addition, compound 2e showed remarkable inactivation activity against Tobacco mosaic virus (TMV), with an EC50 value of 44.3 mu g mL(-1), which was superior to that of ningnanmycin (120.6 mu g mL(-1)). Microscale thermophoresis (MST) also showed that the binding of compounds 2e and 2h to Tobacco mosaic virus coat protein (TMV-CP) yielded K-d values of 0.270 and 0.301 mu mol L-1, which are better than that of ningnanmycin (0.596 mu mol L-1). At the same time, molecular docking studies for 2e and 2h with TMV-CP (PDB code: ; 1EI7) showed that the compound was embedded well in the pocket between the two subunits of TMV-CP in each case. These results suggested that chalcone derivatives containing a thiophene sulfonate group may be considered as activators in the design of antibacterial and antiviral agents.

About Chalcone, If you have any questions, you can contact Guo, T; Xia, ROJ; Chen, M; He, J; Su, SJ; Liu, LW; Li, XY; Xue, W or concate me.. Safety of Chalcone

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Product Details of 94-41-7. I found the field of Chemistry very interesting. Saw the article Boron-Catalyzed Dehydrative Friedel-Crafts Alkylation of Arenes Using beta-Hydroxyl Ketone as MVK Precursor published in 2021.0, Reprint Addresses Tang, XY (corresponding author), Huazhong Univ Sci & Technol, Sch Chem & Chem Engn, 1037 Luoyu Rd, Wuhan 430074, Peoples R China.; Tang, XY (corresponding author), Huazhong Univ Sci & Technol, Hubei Key Lab Bioinorgan Chem & Mat Med, 1037 Luoyu Rd, Wuhan 430074, Peoples R China.. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone.

Boron-catalyzed environmentally benign dehydrative Friedel-Crafts alkylation of indole/pyrrole and aniline derivatives with beta-hydroxyl ketones has been developed for the first time. This method provides an efficient and green replacement of toxic and unstable methyl vinyl ketone (MVK) by safer and cheaper beta-hydroxyl ketone. The reaction features easy operation, wide substrate scope and significantly, only water is formed as by-product.

Product Details of 94-41-7. About Chalcone, If you have any questions, you can contact San, HH; Huang, J; Aye, SL; Tang, XY or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Application In Synthesis of Chalcone. In 2020.0 ORG CHEM FRONT published article about C-H-AMINATION; METAL-FREE; ASYMMETRIC-SYNTHESIS; COUPLING REACTIONS; BOND-FORMATION; VISIBLE-LIGHT; C-SP3-H BONDS; FUNCTIONALIZATION; SUBSTITUTION; REACTIVITY in [Tan, Chen; Liu, Xinyuan; Jia, Huanxin; Huang, Sihan; Wang, Jingwen; Tan, Jiajing] Beijing Univ Chem Technol, Coll Chem, Dept Organ Chem, Beijing 100029, Peoples R China; [Liu, Yongguo] BTBU, Beijing Key Lab Flavor Chem, Beijing 100048, Peoples R China; [Xu, Kun] Nanyang Normal Univ, Coll Chem & Pharmaceut Engn, Nanyang 473061, Henan, Peoples R China in 2020.0, Cited 80.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

Aziridines are ubiquitous in bioactive molecules and often serve as key synthetic building blocks. We report herein an intramolecular KI/TBHP mediated oxidative dehydrogenative C(sp(3))-H amination reaction to synthesize a diverse array of trans-2,3-disubstituted aziridines in good yields under mild conditions. The synthetic utility of this protocol was further highlighted by a one-pot, two-step synthesis of unprotected aziridines.

About Chalcone, If you have any questions, you can contact Tan, C; Liu, YG; Liu, XY; Jia, HX; Xu, K; Huang, SH; Wang, JW; Tan, JJ or concate me.. Application In Synthesis of Chalcone

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Recently I am researching about PHENOLIC CONSTITUENTS; MEDICINAL-PLANTS; LICORICE ROOT; ISOFLAVONOIDS; ANTIOXIDANT; COMPONENTS, Saw an article supported by the State Key Program of National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81430095]. Category: thiazolidines. Published in SPRINGER JAPAN KK in TOKYO ,Authors: Cheng, M; Ding, LQ; Kan, HF; Zhang, HM; Jiang, BK; Sun, YJ; Cao, SJ; Li, W; Koike, K; Qiu, F. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone

Two new flavonoid glycosides, 2 ‘,4 ‘-dihydroxydihydrochalcone-4-O-beta-d-glucopyranoside (1) and medicarpin-3-O-beta-d-apiofuranosyl (1 -> 2)-beta-d-glucopyranoside (2), together with 34 known flavonoids were isolated from the 75% EtOH extract of the dried roots of Glycyrrhiza uralensis Fisch. Their structures were elucidated on the basis of spectroscopic analyses. The flavonoids were classified into ten sub-types, namely, dihydrochalcone (1), pterocarpans (2-4), flavones (5-6), flavanones (7-11), chalcones (12-15), retro-chalcones (16-18), isoflavans (19-21), isoflavones (22-28), 3-arylcoumarins (29-30), and coumestans (31-36). The isolated flavonoids were evaluated for in vitro hepatoprotective activity against d-galactosamine-induced toxicity in human hepatoma HepG2 cells.

About Chalcone, If you have any questions, you can contact Cheng, M; Ding, LQ; Kan, HF; Zhang, HM; Jiang, BK; Sun, YJ; Cao, SJ; Li, W; Koike, K; Qiu, F or concate me.. Category: thiazolidines

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

An article Chemoselective transfer hydrogenation of alpha,beta-unsaturated carbonyls catalyzed by a reusable supported Pd nanoparticles on biomass-derived carbon WOS:000458222300017 published article about ASYMMETRIC TRANSFER HYDROGENATION; N-HETEROCYCLIC CARBENE; HIGHLY EFFICIENT; COMPLEXES; KETONES; RUTHENIUM; NITROARENES; REDUCTION; IRIDIUM; RHODIUM in [Song, Tao; Duan, Yanan; Yang, Yong] Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China in 2019.0, Cited 36.0. COA of Formula: C15H12O. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7

We herein report highly chemoselective transfer hydrogenation of alpha,beta-unsaturated carbonyl compounds to saturated carbonyls with formic acid as a hydrogen donor over a stable and recyclable heterogeneous Pd nano particles (NPs) on N,O-dual doped hierarchical porous biomass-derived carbon. The synergistic effect between Pd NPs and incorporated heteroatoms on carbon plays a critical role on promoting the reaction efficiency. A series of alpha,beta-aromatic and aliphatic unsaturated carbonyl compounds was selectively reduced to their corresponding saturated carbonyls in up to 97% isolated yields with good tolerance of various functional groups. In addition, the catalyst can be successively reused for at least 6 times without significant loss in reaction efficiency.

About Chalcone, If you have any questions, you can contact Song, T; Duan, YA; Yang, Y or concate me.. COA of Formula: C15H12O

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Category: thiazolidines. In 2019.0 J ORG CHEM published article about ORGANIC SULFUR-COMPOUNDS; SUFEX CLICK CHEMISTRY; ASYMMETRIC EPOXIDATION; SUPEROXIDE ANION; SULFONIC PERACIDS; PRACTICAL METHOD; METAL-FREE; OXIDATION; SELECTIVITY; ACTIVATION in [Ai, Chengmei; Zhu, Fuyuan; Wang, Yanmei; Yan, Zhaohua; Lin, Sen] Nanchang Univ, Coll Chem, Nanchang 330031, Jiangxi, Peoples R China in 2019.0, Cited 60.0. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

An inexpensive, mild, and highly efficient epoxidation protocol has been developed involving bubbling SO2F2 gas into a solution of olefin, 30% aqueous hydrogen peroxide, and 4 N aqueous potassium carbonate in 1,4-dioxane at room temperature for 1 h with the formation of the corresponding epoxides in good to excellent yields. The novel SO2F2/H2O2/K2CO3 epoxidizing system is suitable to a variety of olefinic substrates including electron-rich and electron-deficient ones.

About Chalcone, If you have any questions, you can contact Ai, CM; Zhu, FY; Wang, YM; Yan, ZH; Lin, S or concate me.. Category: thiazolidines

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

COA of Formula: C15H12O. Zhang, GD; Hu, ZY; Bertoli, G; Goossen, LJ in [Zhang, Guodong; Hu, Zhiyong; Bertoli, Giulia; Goossen, Lukas J.] Ruhr Univ Bochum, Fak Chem & Biochem, Univ Str 150, D-44801 Bochum, Germany published Iridium-Catalyzed Synthesis of Substituted Indanones from Aromatic Carboxylates and Unsaturated Ketones in 2019, Cited 67. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7.

A catalytic annulation is presented that provides straightforward, modular synthetic access to 3-substituted indanones from benzoic acids and alpha,beta-unsaturated ketones. It is catalyzed by a bimetallic Ir/In system and proceeds via hydroarylation followed by Claisen condensation and optional retro-Claisen deacylation. The annulation may be combined into a one-pot procedure with the synthesis of the unsaturated ketone substrates from aldehydes and acetone. Two complementary reaction protocols are provided that are applicable to diversely functionalized electron-rich and electron-poor substrates.

COA of Formula: C15H12O. About Chalcone, If you have any questions, you can contact Zhang, GD; Hu, ZY; Bertoli, G; Goossen, LJ or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

An article Methylene-Linked Bis-NHC Half-Sandwich Ruthenium Complexes: Binding of Small Molecules and Catalysis toward Ketone Transfer Hydrogenation WOS:000636740800018 published article about N-HETEROCYCLIC CARBENES; ASYMMETRIC TRANSFER HYDROGENATION; SECONDARY ALCOHOLS; HYDRIDE COMPLEXES; CP-ASTERISK; LIGANDS; REACTIVITY; BEARING; ALKYLATION in [Manuel Botubol-Ares, Jose; Cordon-Ouahhabi, Safa; Moutaoukil, Zakaria; Collado, Isidro G.] Univ Cadiz, Fac Ciencias, Dept Quim Organ INBIO, Cadiz 11510, Spain; [Jimenez-Tenorio, Manuel; Carmen Puerta, M.; Valerga, Pedro] Univ Cadiz, Fac Ciencias, Dept Ciencia Mat & Ingn Met & Quim Inorgan INBIO, Cadiz 11510, Spain in 2021.0, Cited 83.0. Safety of Chalcone. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7

The complex [Cp*RuCl(COD)] reacts with LH2Cl2 (L = bis(3-methylimidazol-2-ylidene)) and LiBun in tetrahydrofuran at 65 degrees C furnishing the bis-carbene derivative [Cp*RuCl(L)] (2). This compound reacts with NaBPh4 in MeOH under dinitrogen to yield the labile dinitrogen-bridged complex [{Cp*Ru(L)}(2)(mu-N-2)][BPh4](2) (4). The dinitrogen ligand in 4 is readily replaced by a series of donor molecules leading to the corresponding cationic complexes [Cp*Ru(X)(L)][BPh4] (X = MeCN 3, H-2 6, C2H4 8a, CH2CHCOOMe 8b, CHPh 9). Attempts to recrystallize 4 from MeNO2/EtOH solutions led to the isolation of the nitrosyl derivative [Cp*Ru(NO)(L)][BPh4](2) (5), which was structurally characterized. The allenylidene complex [Cp*Ru=C=C=CPh2 (L)][BPh4] (10) was also obtained, and it was prepared by reaction of 2 with HC CC(OH)Ph-2 and NaBPh4 in MeOH at 60 degrees C. Complexes 3, 4, and 6 are efficient catalyst precursors for the transfer hydrogenation of a broad range of ketones. The dihydrogen complex 6 has proven particularly effective, reaching TOF values up to 455 h(-1) at catalyst loadings of 0.1% mol, with a high functional group tolerance on the reduction of a broad scope of aryl and aliphatic ketones to yield the corresponding alcohols.

Safety of Chalcone. About Chalcone, If you have any questions, you can contact Botubol-Ares, JM; Cordon-Ouahhabi, S; Moutaoukil, Z; Collado, IG; Jimenez-Tenorio, M; Puerta, MC; Valerga, P or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

Authors Minami, Y; Konishi, A; Yasuda, M in AMER CHEMICAL SOC published article about CROSS-ALDOL REACTION; BAYLIS-HILLMAN REACTION; REGIOSELECTIVE SYNTHESIS; ALDEHYDES; REACTIVITY; SILYLENE; ALKYNES; IDENTIFICATION; COORDINATION; INHIBITORS in [Minami, Yohei; Konishi, Akihito; Yasuda, Makoto] Osaka Univ, Grad Sch Engn, Dept Appl Chem, 2-1 Yamadaoka, Suita, Osaka 5650871, Japan; [Konishi, Akihito] Osaka Univ, Grad Sch Engn, Ctr Atom & Mol Technol, 2-1 Yamadaoka, Suita, Osaka 5650871, Japan in 2019.0, Cited 52.0. Recommanded Product: Chalcone. The Name is Chalcone. Through research, I have a further understanding and discovery of 94-41-7

The synthesis of alpha-alkenyl alpha,beta-unsaturated ketones using germanium(II) salts is reported. Oxagermacycles derived from alpha,beta-unsaturated ketones with germanium(II) salts and aldehydes can be transformed into a-alkenyl a 6-unsaturated ketones. Ammonium salts promoted the elimination of Ge(II) species to afford the two classes of alpha-alkenyl alpha,beta-unsaturated ketones in good yields. The alpha-alkenyl alpha,beta-unsaturated ketones are precursors for multisubstituted heterocycles.

Recommanded Product: Chalcone. About Chalcone, If you have any questions, you can contact Minami, Y; Konishi, A; Yasuda, M or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com

I found the field of Chemistry very interesting. Saw the article A highly efficient Hg(OTf)(2)-mediated Sakurai-Hosomi allylation of N-tert-butyloxycarbonylamino sulfones, aldehydes, fluoroalkyl ketones and alpha,beta-unsaturated enones using allyltrimethylsilane published in 2019.0. SDS of cas: 94-41-7, Reprint Addresses Zhou, Y; Zhou, J (corresponding author), Guiyang Univ Chinese Med, Coll Pharm, Guiyang 550025, Guizhou, Peoples R China.; Zhou, J (corresponding author), East China Normal Univ, Shanghai Key Lab Green Chem & Chem Proc, Shanghai Engn Res Ctr Mol Therapeut & New Drug De, 3663N Zhongshan Rd, Shanghai 200062, Peoples R China.; Zhou, J (corresponding author), Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China.. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone

It is reported that cheap and easily available Hg(OTf)(2) can efficiently mediate the Sakurai-Hosomi reaction of N-tert-butyloxycarbonyl (Boc) amino sulfones, aldehydes, and alpha-fluoroalkyl ketones using allyltrimethylsilane, with the catalyst loading down to 0.5-5.0 mol%, enabling the facile access to synthetically valuable homoallylic alcohols or amines, respectively. A chemoselective 1,4-allylation of alpha,beta-unsaturated enones is also achieved under the catalysis of 5.0 mol% Hg(OTf)(2). In most cases, Hg(OTf)(2) exhibited intriguing properties superior to those of commonly used metal Lewis acids for such reactions, suggesting that mercury catalysis is worthwhile to explore.

SDS of cas: 94-41-7. About Chalcone, If you have any questions, you can contact Gong, Y; Cao, ZY; Shi, YB; Zhou, F; Zhou, Y; Zhou, J or concate me.

Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com