Tag: M.W:100-200

Synthetic Route of C9H13NO2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, is researched, Molecular C9H13NO2, CAS is 2199-44-2, about Molecular Rectangle Formed by Head-to-tail Self-Assembly of 1-(Dipyrrin-2-yl)-1′-(dipyrrin-3-yl)methane. Author is Yang, Lanying; Zhang, Yi; Chen, Qingqi; Ma, Jin Shi.

1-(Dipyrrin-2-yl)-1′-(dipyrrin-3-yl)methane (I), the N-confused analog of biladiene-ac, was prepared by condensation of 2,3′-dipyrromethane with two mols. of 2-formylpyrrole in CH2Cl2 in the presence of HBr. Self-assembly of the ligand with Zn(II) in CH2Cl2 and MeOH offers a dinuclear dimeric complex with a ligand:metal ratio of 2:2. X-ray crystal structure anal. reveals two ligands bound through a head-to-tail pattern to two Zn centers to form a severely distorted helical conformation, which has the shape of a rectangle.

I hope my short article helps more people learn about this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate)Synthetic Route of C9H13NO2. Apart from the compound(2199-44-2), you can read my other articles to know other related compounds.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Khan, Shafiq A.; Plieninger, Hans researched the compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate( cas:2199-44-2 ).Application In Synthesis of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate.They published the article 《Synthesis of a tripyrrin-14-carboxylic acid with two neopentyl groups》 about this compound( cas:2199-44-2 ) in Chemische Berichte. Keywords: tripyrrincarboxylic acid; metal complex tripyrrincarboxylic acid. We’ll tell you more about this compound (cas:2199-44-2).

Tripyrrincarboxylic acid I was prepared from pyrrole II by condensation with Me3CCHO and HI to give iodo derivative III which was reduced to IV. SO2Cl2 reacted with IV to give V, which was hydrolyzed to aldehydic acid VI. This condensed with 3,4-dimethyl-3-pyrrolin-2-one to pyrromethenone VII, which was decarboxylated to VIII. VI condensed with VIII to give I. Metal complexes of I are soluble in most organic solvents even after crystallization

I hope my short article helps more people learn about this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate)Application In Synthesis of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. Apart from the compound(2199-44-2), you can read my other articles to know other related compounds.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Synthetic Route of C9H13NO2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, is researched, Molecular C9H13NO2, CAS is 2199-44-2, about New method for synthesis of (ω-chloroalkyl)pyrroles. Author is Tu, Bin; Wang, Changqi; Ma, Jinshi.

Et 4-(ω-chloroalkyl)-3,5-dimethyl-1H-pyrrole-2-carboxylates (alkyl = Et, Pr, butyl) were prepared in >96% yields from Et 4-(ω-chloroacyl)-3,5-dimethyl-1H-pyrrole-2-carboxylates by treatment with NaBH4 followed by BF3·Et2O in THF. The ω-chloroacyl derivatives were prepared from 2-(ethoxycarbonyl)-3,5-dimethylpyrrole (1) by Friedel-Crafts reaction in >91% yields. 1 Was prepared in one step from 2,4-pentanedione and di-Et aminomalonate or di-Et oximinomalonate according to literature methods.

I hope my short article helps more people learn about this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate)Synthetic Route of C9H13NO2. Apart from the compound(2199-44-2), you can read my other articles to know other related compounds.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Synthesis of pyrrolecarboxaldehydes, published in 1956, which mentions a compound: 2199-44-2, Name is Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, Molecular C9H13NO2, Safety of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate.

HCO-NMe2 (I) (23.89 g.) and 58.25 g. POCl3 warmed after 10 min. to 60°, treated dropwise in 1.5 hrs. with 18 g. 2,4-dimethylpyrrole in an equal volume of I, the mixture stirred 1 hr. at 60°, poured into 333 g. ice and 245 g. fused NaOAc, the mixture boiled, cooled, extracted with Et2O, the extract evaporated free from Et2O and made alk. with powd. Na2CO3, filtered, and the residual product (II) dried. Further extraction of the filtrate with Et2O gave another 0.69 g. II. II boiled in petr. ether, the solution purified with C, filtered and cooled gave 0.6 g. (crude) 2,4-dimethyl-3,5-pyrroledicarboxaldehyde, m. 165-6° (from H2O), and 9.6 g. (crude) 2,4-dimethyl-5-pyrrolecarboxaldehyde, m. 89-90° (from H2O). Similarly, I and POCl3 at 60°, treated dropwise with stirring with 2,4-dimethyl-8-ethylpyrrole gave 2,4-dimethyl-3-ethyl-5-pyrrolecarboxaldehyde, m. 105-6°. In the same way, 1.79 g. I and 4.37 g. POCl3 treated with 1.35 g. 2,3,4-trimethylpyrrole gave 0.3 g. 2,3,4-trimethyl-5-pyrrolecarboxaldehyde, m. 147°; 2.6 g. I and 6.32 g. POCl3 with 3 g. Et 2,4-dimethyl-3-pyrrolecarboxylate in I yielded Et 2,4-dimethyl-5-formyl-3-pyrrolecarboxylate, m. 165°; 8.6 g. I and 21 g. POCl3 with 10 g. Et 2,4-dimethyl-5-pyrrolecarboxylate and 10 g. I produced 11.2 g. Et 2,4-dimethyl-3-formyl-5-pyrrolecarboxylate, m. 145°. Heating 20 g. 2,4-dimethyl-5-carbethoxy-3-pyrrolecarboxylate at 200° with 200 g. quinoline and 2 g. finely divided pure Cu to cessation of CO2 evolution, cooling, filtering, acidifying the filtrate with 50% HCl, filtering, washing the precipitate with H2O, and drying gave 11.2 g. Et 2,4-dimethyl-5-pyrrolecarboxylic acid, m. 122°.

I hope my short article helps more people learn about this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate)Safety of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. Apart from the compound(2199-44-2), you can read my other articles to know other related compounds.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Computed Properties of C9H13NO2. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, is researched, Molecular C9H13NO2, CAS is 2199-44-2, about Fluoropyrroles and tetrafluoroporphyrins.

Photolysis of the pyrrole-β-diazonium tetrafluoroborate I (R = N2+BF4-) gave the β-fluoropyrrole I (R = F) which was oxidized to the alc. II. Treatment of II with K3Fe(CN)6 or Cu(OAc)2 gave the fluoroporphyrins III (M = 2H, Cu) resp.

I hope my short article helps more people learn about this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate)Computed Properties of C9H13NO2. Apart from the compound(2199-44-2), you can read my other articles to know other related compounds.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Decarboxylation and formylation of certain pyrrole derivatives》. Authors are Chu, Edith Ju-Hwa; Chu, T. C..The article about the compound:Ethyl 3,5-Dimethyl-2-pyrrolecarboxylatecas:2199-44-2,SMILESS:O=C(C1=C(C)C=C(C)N1)OCC).Recommanded Product: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. Through the article, more information about this compound (cas:2199-44-2) is conveyed.

H2NCH2CH2OH (I) is used as decarboxylation agent for substituted carboxypyrroles. Adding 28.5 g. AcCH2CO2Et to Et α-nitroso-α-benzoylacetate (from 38.5 g. BzCH2CO2Et), then adding gradually 28.5 g. Zn dust with gentle boiling, refluxing the mixture 2 hrs., and pouring it into H2O give 63% 2-methyl-4-phenyl-3,5-dicarbethoxypyrrole, colorless prisms, m. 124-5°. 2,4-Dimethyl-3-carboxy-5-carbethoxypyrrole (II), 85%, fine prisms, m. 272° (decomposition), and 2-methyl-4-phenyl-3-carboxy-5-carbethoxypyrrole (III), 78%, platelets, m. 220° (decomposition) are prepared by partial saponification of the corresponding diesters. Refluxing 21.1 g. II and 12.2 g. I 1 hr. and pouring the mixture into H2O give 90% 2,4-dimethyl-5-carbethoxypyrrole (IV), prisms, m. 124.5-5°; similarly, III gives 84% 2-methyl-4-phenyl-5-carbethoxypyrrole, needles, m. 134.5-5°. Gradually adding 15.4 g. POCl3 to 13.4 g. IV and 7.3 g. HCONMe2, refluxing the mixture 2 hrs., pouring it into H2O, and neutralizing it with NaOAc give 95% 2,4-dimethyl-3-formyl-5-carbethoxypyrrole, needles, m. 145-5.5° (oxime, m. 199-200°; semicarbazone, decompose at about 275°). 2-Methyl-4-phenyl-3-formyl-5-carbethoxypyrrole, prepared similarly in 97% yield, prisms, m. 144.5-5° (oxime, 96%, plates, m. 210-11°; semicarbazone, needles, decompose at about 280° with sublimation).

I hope my short article helps more people learn about this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate)Recommanded Product: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. Apart from the compound(2199-44-2), you can read my other articles to know other related compounds.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, is researched, Molecular C9H13NO2, CAS is 2199-44-2, about Fluoropyrroles and tetrafluoroporphyrins, the main research direction is fluoropyrrole preparation cyclocondensation; fluoroporphyrin; porphyrin tetrafluoro.HPLC of Formula: 2199-44-2.

Photolysis of the pyrrole-β-diazonium tetrafluoroborate I (R = N2+BF4-) gave the β-fluoropyrrole I (R = F) which was oxidized to the alc. II. Treatment of II with K3Fe(CN)6 or Cu(OAc)2 gave the fluoroporphyrins III (M = 2H, Cu) resp.

There is still a lot of research devoted to this compound(SMILES：O=C(C1=C(C)C=C(C)N1)OCC)HPLC of Formula: 2199-44-2, and with the development of science, more effects of this compound(2199-44-2) can be discovered.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Acta Crystallographica, Section E: Structure Reports Online called Ethyl 3,5-dimethyl-1H-pyrrole-2-carboxylate, Author is Arranja, Claudia T.; Ramos Silva, Manuela; Matos Beja, Ana; Ferreira, Ana F. P. V.; Sobral, Abilio J. F. N., which mentions a compound: 2199-44-2, SMILESS is O=C(C1=C(C)C=C(C)N1)OCC, Molecular C9H13NO2, Name: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate.

In the title compound, C9H13NO2, there are two independent mols. per asym. unit. The mols. are very similar and almost planar, with the ethoxycarbonyl group anti to the pyrrole N atom. The two independent mols. are joined into dimeric units by strong hydrogen bonds between NH groups and carbonyl O atoms. Crystallog. data are given.

There is still a lot of research devoted to this compound(SMILES：O=C(C1=C(C)C=C(C)N1)OCC)Name: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, and with the development of science, more effects of this compound(2199-44-2) can be discovered.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Decarboxylation and formylation of certain pyrrole derivatives》. Authors are Chu, Edith Ju-Hwa; Chu, T. C..The article about the compound:Ethyl 3,5-Dimethyl-2-pyrrolecarboxylatecas:2199-44-2,SMILESS:O=C(C1=C(C)C=C(C)N1)OCC).Reference of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. Through the article, more information about this compound (cas:2199-44-2) is conveyed.

H2NCH2CH2OH (I) is used as decarboxylation agent for substituted carboxypyrroles. Adding 28.5 g. AcCH2CO2Et to Et α-nitroso-α-benzoylacetate (from 38.5 g. BzCH2CO2Et), then adding gradually 28.5 g. Zn dust with gentle boiling, refluxing the mixture 2 hrs., and pouring it into H2O give 63% 2-methyl-4-phenyl-3,5-dicarbethoxypyrrole, colorless prisms, m. 124-5°. 2,4-Dimethyl-3-carboxy-5-carbethoxypyrrole (II), 85%, fine prisms, m. 272° (decomposition), and 2-methyl-4-phenyl-3-carboxy-5-carbethoxypyrrole (III), 78%, platelets, m. 220° (decomposition) are prepared by partial saponification of the corresponding diesters. Refluxing 21.1 g. II and 12.2 g. I 1 hr. and pouring the mixture into H2O give 90% 2,4-dimethyl-5-carbethoxypyrrole (IV), prisms, m. 124.5-5°; similarly, III gives 84% 2-methyl-4-phenyl-5-carbethoxypyrrole, needles, m. 134.5-5°. Gradually adding 15.4 g. POCl3 to 13.4 g. IV and 7.3 g. HCONMe2, refluxing the mixture 2 hrs., pouring it into H2O, and neutralizing it with NaOAc give 95% 2,4-dimethyl-3-formyl-5-carbethoxypyrrole, needles, m. 145-5.5° (oxime, m. 199-200°; semicarbazone, decompose at about 275°). 2-Methyl-4-phenyl-3-formyl-5-carbethoxypyrrole, prepared similarly in 97% yield, prisms, m. 144.5-5° (oxime, 96%, plates, m. 210-11°; semicarbazone, needles, decompose at about 280° with sublimation).

From this literature《Decarboxylation and formylation of certain pyrrole derivatives》,we know some information about this compound(2199-44-2)Reference of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, but this is not all information, there are many literatures related to this compound(2199-44-2).

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Sulfur derivatives in the pyrrole series, published in 1973, which mentions a compound: 2199-44-2, mainly applied to pyrrolyl sulfide; thiocarboxamide pyrrole, Synthetic Route of C9H13NO2.

Reaction of 2,4-dimethyl-5-(ethoxycarbonyl)pyrrole (I) with SO2 in the presence of EtBr and AlCl3 or in CH2Cl2 containing AlCl3 gave the sulfide II or the sulfoxide III, resp. Successive reaction of SCl2 with MeOH and 2-methyl-3-(ethoxycarbonyl pyrrole gave the disulfide IV. Addition of EtSH to tris[2-methyl-3-(ethoxycarbonyl)-5-pyrrolyl]methane gave the sulfide V. Addition of p-tolysulfonyl isothiocyanate to I gave the derivative VI.

From this literature《Sulfur derivatives in the pyrrole series》,we know some information about this compound(2199-44-2)Synthetic Route of C9H13NO2, but this is not all information, there are many literatures related to this compound(2199-44-2).

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com