The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Formula: C17H26O4, 83237-15-4, Name is 3-(3,5-Di-tert-butyl-1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)propanoic acid, SMILES is O=C(CCC1(C=C(C(C)(C)C)C(=O)C(C(C)(C)C)=C1)O)O, in an article , author is Noorulla, K. M., once mentioned of 83237-15-4.
Molecular modeling of drug-pathophysiological Mtb protein targets: Synthesis of some 2-thioxo-1,3-thiazolidin-4-one derivatives as anti-tubercular agents
Twenty novel 2-thioxo-1, 3-thiazolidin-4-one derivatives (5a-5t) were synthesized and evaluated for their antitubercular activity. The structure of the compounds was confirmed by IR, NMR and Mass Spectroscopy methods. In addition, single-crystal X-ray diffraction was performed for compound 5a. All the synthesized compounds were screened for their in-vitro antimycobacterial activity against MTB (H37RV, ATCC No: 27294) by Alamar Blue assay method. Compounds 5r, 5k, 5t displayed most potent in-vitro activity with MICs of 0.05, 0.1, 0.2 mu g/ml concentrations respectively which are comparatively potent than the standards. Molecular docking and dynamics simulations were performed to find out the plausible mechanism of the titled compounds. (C) 2017 Elsevier B.V. All rights reserved.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 83237-15-4, you can contact me at any time and look forward to more communication. Formula: C17H26O4.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com