3-Aminorhodanine, cas is 1438-16-0, it is a common heterocyclic compound, the thiazolidine compound, its synthesis route is as follows.
EXAMPLE 30 A solution of rhodanine-3-carbamoylsulphonyl chloride which is obtained if a solution of 3.11 g of 3-aminorhodanine in 50 ml of acetonitrile is added to a solution of 1.8 ml of chlorosulphonylisocyanate in 50 ml acetonitrile and the mixture is stirred for 40 minutes at 25 C, is reacted, analogously to Example 5, with a silyl ester solution as in Example 5 (approx. 1.5 mmols of silyl ester), and worked up. The resulting crude product, in acetone solution, is decolourised with active charcoal and then converted by means of sodium alpha-ethylhexanoate into the sodium salt of 6-[D-alpha-(rhodanine-3-carbamylsulphamylamino)-phenylacetamido]-penicillanic acid. In a thin layer chromatogram on silica gel, Rf52 = 0.56; Rf96 = 0.76; Rf100 = 0.20; Rf110 = 0.28. [alpha]D20 = + 110 +- 1 (c = 1 in 0.5 N NaHCO3)., 1438-16-0
With the rapid development of chemical substances, we look forward to future research findings about 3-Aminorhodanine
Reference£º
Patent; Ciba-Geigy Corporation; US3996208; (1976); A;,
Thiazolidine – Wikipedia
Thiazolidine – ScienceDirect.com