Mercaptothioalkanoic acids. III. Reactions of mercaptothioalkanoic acids with isocyanates was written by Satsumabayashi, Sadayoshi;Nakayama, Junichi. And the article was included in Nippon Shika Daigaku Kiyo, Ippan Kyoiku-kei in 1981.Application In Synthesis of 3-Methylthiazolidine-2,4-dione This article mentions the following:
HSCH2COSH was treated with RNCO (R = Me, Me2CH, p-ClC6H4, Et, H, p-MeC6H4) to give RNHCOCH2SH (R = Me, Me2CH, p-ClC4H4, Et, Ph, p-MeC4H4) and the thiazoles I (R = Me, Me2CH, Et). HSCH2CH2COSH and RNCO (R as above) gave RNHCOCH2CH2SH. In the experiment, the researchers used many compounds, for example, 3-Methylthiazolidine-2,4-dione (cas: 16312-21-3Application In Synthesis of 3-Methylthiazolidine-2,4-dione).
3-Methylthiazolidine-2,4-dione (cas: 16312-21-3) belongs to thiazolidine derivatives. Thiazolidine derivatives have been found to exhibit very prominent anti-inflammatory and anti-nociceptive activity. Thiazolidines unsubstituted on the nitrogen atom are readily hydrolyzed by boiling aqueous solutions of acids or bases and the dissociation is complete in the presence of a compound reacting with one of the cleavage products.Application In Synthesis of 3-Methylthiazolidine-2,4-dione
Referemce:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com