Properties and Exciting Facts About 108-59-8

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In an article, author is Ukhin, Lev Yu., once mentioned the application of 108-59-8, Quality Control of Dimethylmalonate, Name is Dimethylmalonate, molecular formula is C5H8O4, molecular weight is 132.1146, MDL number is MFCD00008460, category is thiazolidines. Now introduce a scientific discovery about this category.

Novel reactions of ninhydrin oxime with mercaptoalkanoic acids

Ninhydrin oxime and mercaptoalkanoic acids in the presence of trifluoroacetic acid form 2,2 ‘-spiranes incorporating indane-1,3-dione and 3-hydroxy-1,3-thiazolidin-4-one or 3-hydroxytetrahydro-1,3-thiazin-4-one moieties. On heating in acetic anhydride, the same reactants undergo replacement of oxime hydroxy group by sulfur thus affording thiooxime-containing alkanoic acids.

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Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com