Derivatives of 2-thiazolidinecarboxylic acid was written by Pazenko, Z. N.. And the article was included in Ukrains’kii Khemichnii Zhurnal in 1958.Recommanded Product: Thiazolidine-2-carboxylic acid This article mentions the following:
(EtO)2CHCO2H (I) and H2N(CH2)2SH, m. 97°, (from (CH2)2NH and H2S) form in EtOH 2-thiazolidinecarboxylic acid (II), decompose 203°. The Et ester of I forms similarly that of II, m. 37°, HCl salt m. 207-9°, and an unidentified compound, 9.36% N, m. 230°. Cl2CHCO2Me forms the Me ester of II, b4 8.9°, m. 25°. II, (CH2)2O, and BF3 in Et2O form 3-β-hydroxyethyl-2-thiazolidinecarboxylic acid δ-lactone, m. 87-9°. MeCOCO2H and MeCOCO2Et and H2N(CH2)2SH form the 2-Me derivative of II and its Et ester, m. 192-5° and b4 72-5°, resp. In the experiment, the researchers used many compounds, for example, Thiazolidine-2-carboxylic acid (cas: 16310-13-7Recommanded Product: Thiazolidine-2-carboxylic acid).
Thiazolidine-2-carboxylic acid (cas: 16310-13-7) belongs to thiazolidine derivatives. Thiazolidine derivatives have been found to exhibit very prominent anti-inflammatory and anti-nociceptive activity. Thiazolidine-2,4-dione (TZD) is an important derivative of thiazolidine with a sulfur and nitrogen atom in positions 1 and 3, and carbonyl in position 4 of the ring. These derivatives have a wide range of medicinal applications such as antiviral, antimicrobial, anticonvulsant, antiinflammatory, and antimalarial activities.Recommanded Product: Thiazolidine-2-carboxylic acid
Referemce:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com