Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 1823-59-2, Name is 5,5′-Oxybis(isobenzofuran-1,3-dione), molecular formula is C16H6O7. In an article, author is Marri, Srinivas,once mentioned of 1823-59-2, SDS of cas: 1823-59-2.
Synthesis and pharmacological evaluation of 3-(3,5-dimethylisoxazol-4-yl)-2-arylthiazolidin-4-ones as potential antioxidant, anti-inflammatory and analgesic agents
3-(3,5-Dimethylisoxazol-4-yl)-2-arylthiazolidin-4-ones 3a-1 have been synthesized from 4-amino-3,5-dimethylisoxazole 1 by condensation with aromatic aldehydes, followed by cyclization with mercaptoacetic acid in excellent yields, and have been evaluated for in vitro antioxidant activity. Based on potential antioxidant property, compounds 3c, 3e, 3h, 3i, and 3l have been screened for in vivo anti-inflammatory and analgesic activity. Molecular docking studies have also been carried out to balance the bioactivity results. From these results it is evident that the compound 3c shows potential anti-inflammatory and analgesic activity.
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Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com