Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 922-67-8, Name is Methyl propiolate, molecular formula is C4H4O2, belongs to thiazolidines compound, is a common compound. In a patnet, author is das Neves, Adriana M., once mentioned the new application about 922-67-8, Safety of Methyl propiolate.
Synthesis of Novel Thiazolidin-4-ones and Thiazinan-4-ones Analogous to Rosiglitazone
This work reports the synthesis of thiazolidin-4-ones and thiazinan-4-ones analogous to rosiglitazone, a potent antidiabetic drug. The desired compounds were synthesized with moderate to good yields by one-pot reactions between different primary amines, mercaptoacetic or mercaptopropionic acids, and the 4-(2-(methyl(pyridin-2-yl)amino)ethoxy)benzaldehyde. The cyclocondensation reactions were carried out for 20 h, and all the products were characterized by H-1 and C-13 nuclear magnetic resonance spectroscopy, mass spectrometry, and one example by X-ray diffraction.
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Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com