The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Chloro-7-nitro-1H-benzo[d]imidazole( cas:15965-55-6 ) is researched.Category: thiazolidine.Vivarelli, Piero; Taddei, Ferdinando published the article 《Benzimidazoles. Prototropic equilibriums and product distribution from methylation of substituted 2-chlorobenzimidazoles》 about this compound( cas:15965-55-6 ) in Gazzetta Chimica Italiana. Keywords: benzimidazole chloro methylation; methylation chlorobenzimidazole; tautomerization chlorobenzimidazole. Let’s learn more about this compound (cas:15965-55-6).
Methylation of the benzimidazoles I (R = Me, MeO, Cl, NO2, R1 = H) gave equal amounts of II and III. Methylation of I (R = H, R1 = Me, MeO, Cl, NO2) gave II and a larger amount of III. The ratio of tautomers was determined by NMR.
As far as I know, this compound(15965-55-6)Category: thiazolidine can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com