In an article, author is Kumari, Maddineni Aruna, once mentioned the application of 94-41-7, Category: thiazolidines, Name is Chalcone, molecular formula is C15H12O, molecular weight is 208.2552, MDL number is MFCD00003082, category is thiazolidines. Now introduce a scientific discovery about this category.
SYNTHESIS AND CHARACTERIZATIONOF NOVEL THIAZOLIDINONE DERIVATIVES OF C-MANNICH BASES
The present synthesis involves the introduction of C-Mannich bases on 4-thiazolidinone derivatives. Thiazolidinone derivatives (2a-e) were prepared by treating thiosemicarbazones (1a-e) with bromoethyl acetate and sodium acetate in DMF. C-Mannich bases (4a-b) were prepared by treating propargyl derivative of p-hydroxy benzaldehyde (3) with different secondary amines (piperidine/Morpholine), 40% formaldehyde and Cu (II) acetate in dioxane. These thiazolidinone derivatives and C-Mannich bases are condensed to get the final derivatives (5a-j). All the synthesized compounds were characterized by Mass, H-1 NMR and C-13 NMR spectra.
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Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com