Application In Synthesis of 1,1,1-Triethoxyethane. I found the field of Chemistry very interesting. Saw the article Activity-directed expansion of a series of antibacterial agents published in 2020.0, Reprint Addresses Nelson, A (corresponding author), Univ Leeds, Sch Chem, Leeds LS2 9JT, W Yorkshire, England.; O’Neill, AJ; Nelson, A (corresponding author), Univ Leeds, Astbury Ctr Struct Mol Biol, Leeds LS2 9JT, W Yorkshire, England.; O’Neill, AJ (corresponding author), Univ Leeds, Sch Mol & Cellular Biol, Leeds LS2 9JT, W Yorkshire, England.. The CAS is 78-39-7. Through research, I have a further understanding and discovery of 1,1,1-Triethoxyethane.
The feasibility of using activity-directed synthesis to drive antibacterial discovery was investigated. An array of 220 Pd-catalysed microscale reactions was executed, and the crude product mixtures were evaluated for activity againstStaphylococcus aureus.Scale-up of the hit reactions, purification and evaluation, enabled expansion of a class of antibacterial quinazolinones. The novel antibacterials had MICs from 0.016 mu g mL(-1)(i.e.38 nM) to 2-4 mu g mL(-1)againstS. aureusATCC29213.
About 1,1,1-Triethoxyethane, If you have any questions, you can contact Leggott, A; Clarke, JE; Chow, S; Warriner, SL; O’Neill, AJ; Nelson, A or concate me.. Application In Synthesis of 1,1,1-Triethoxyethane
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com