Research speed reading in 2021. Electric Literature of 7025-19-6, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. In a document type is Article, and a compound is mentioned, 7025-19-6, 3-(4-Oxo-2-thioxothiazolidin-3-yl)propanoic acid, introducing its new discovery.
A catalyst-free Knoevenagel type synthesis of isatinylidenerhodanines is reported starting from substituted isatins and rhodanines. The reaction proceeds spontaneously at room temperature in dimethyl sulfoxide (DMSO), employing a unique macrocyclic intermediate formed through an intramolecular H-bonding. Various substituted isatinylidenerhodanines could be synthesized in good yields.
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Reference：
Quinuclidine – Wikipedia,
Quinuclidine | C7H824N | ChemSpider