New general asymmetric synthesis of versatile γ-alkylated butenolides and its application to expeditious synthesis of the chiral Geissman-Waiss lactones useful for (+)-retronecine synthesis was written by Nagao, Yoshimitsu;Dai, Wei Min;Ochiai, Masahito;Shiro, Motoo. And the article was included in Journal of Organic Chemistry in 1989.Quality Control of (S)-4-Isopropylthiazolidine-2-thione This article mentions the following:
A new strategy for general asym. synthesis of chiral butenolides, e.g. I, is established by utilizing excellent diastereocontrolled alkylation with chiral tin(II) enolate of II at the γ-position of hydroxy butenolides. An efficient utility of the chiral butenolides is exemplified with the expeditious synthesis of the optically pure Geissman-Waiss lactone derivatives III (R = CO2Et, CH2O2CCMe3). In the experiment, the researchers used many compounds, for example, (S)-4-Isopropylthiazolidine-2-thione (cas: 76186-04-4Quality Control of (S)-4-Isopropylthiazolidine-2-thione).
(S)-4-Isopropylthiazolidine-2-thione (cas: 76186-04-4) belongs to thiazolidine derivatives. Thiazolidine motifs are very intriguing heterocyclic five-membered moieties present in diverse natural and bioactive compounds having sulfur at the first position and nitrogen at the third position. Thiazolidine is prepared as it was in its first reported synthesis, by the condensation of cysteamine and formaldehyde. Other thiazolidines may be synthesized by similar condensations. A notable derivative is 4-carboxythiazolidine, derived from formaldehyde and cysteine.Quality Control of (S)-4-Isopropylthiazolidine-2-thione
Referemce:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com