6′-(3-Bromophenyl)-7′-nitro-1′,6′,7′,7a′-tetrahydro-3′H-spiro[indeno[1,2-b]quinoxaline-11,5′-pyrrolo[1,2-c]thiazole] was written by Muthuselvi, C.;Muthu, M.;Athimoolam, S.;Ravikumar, B.;Pandiarajan, S.;Krishnakumar, R. V.. And the article was included in IUCrData in 2018.Safety of Thiazolidine-4-carboxylic acid This article mentions the following:
The title compound, C26H19BrN4O2S, crystallizes in a monoclinic C-centered lattice with eight mols. in the unit cell. The five-membered thiazole and pyrrolidine rings adopt envelope conformations and the bromophenyl and indenoquinoxaline planes are oriented at a dihedral angle of 61.6 (1)° to each other. The mol. structure features an intramol. C-H···N interaction leading to an S(6) ring motif. C(9) and C(10) chains along the c- and b-axis directions form through C-H···Br and C-H···S contacts, resp. In addition, C-H···O and C-H···N hydrogen bonds form inversion dimers with R22(10) and R22(14) motifs, resp. One O atom is disordered over two positions (occupancy ratio 0.63:0.37). In the experiment, the researchers used many compounds, for example, Thiazolidine-4-carboxylic acid (cas: 444-27-9Safety of Thiazolidine-4-carboxylic acid).
Thiazolidine-4-carboxylic acid (cas: 444-27-9) belongs to thiazolidine derivatives. Thiazolidine motifs are very intriguing heterocyclic five-membered moieties present in diverse natural and bioactive compounds having sulfur at the first position and nitrogen at the third position. Open-chain compounds are obtained when thiazolidines are treated with tris(trimethylsilyl)silane in a reaction in which the thiazolidine derivatives act as a source of α-aminoalkyl radicals.Safety of Thiazolidine-4-carboxylic acid
Referemce:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com