A Larock indolization approach to substituted tryptamines was written by Moss, Thomas A.;Lister, Andrew S.;Wang, Jimmy. And the article was included in Tetrahedron Letters in 2017.COA of Formula: C8H15NO5S This article mentions the following:
Substituted tryptamines, an important class of heterocycle in both natural products and medicinal chem., are readily accessible through a Larock indolization approach. The acetylene precursors are in turn routinely accessed as single enantiomers from ring opening of chiral cyclic sulfamidate precursors. Using this two-step protocol, a range of unnatural substituted tryptamines have been synthesized in good yields. In the experiment, the researchers used many compounds, for example, (R)-3-Boc-4-methyl-1,2,3-oxathiazolidine 2,2-Dioxide (cas: 454248-53-4COA of Formula: C8H15NO5S).
(R)-3-Boc-4-methyl-1,2,3-oxathiazolidine 2,2-Dioxide (cas: 454248-53-4) belongs to thiazolidine derivatives. Thiazolidine is a heterocyclic compound with five-membered saturated ring with a thioether group and an amine group in 1 and 3 positions of the ring. In addition, the use of thiazolidines as an inhibitor of tyrosyl-DNA phosphodiesterase Iand influenza neuraminidase, pro-drugs for the treatment of cystinosis, radioprotective against γ-irradiation and as S1P1 receptor agonist has also been reported.COA of Formula: C8H15NO5S
Referemce:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com