Solvolysis kinetics and mechanism of 3-methyl-1,3-thiazolidine-2,4-dione was written by Machacek, Vladimir;Sterba, Vojeslav;Zahradnickova, Helena. And the article was included in Collection of Czechoslovak Chemical Communications in 1981.Recommanded Product: 16312-21-3 This article mentions the following:
The kinetics of base-catalyzed hydrolysis and methanolysis of 3-methyl-1,3-thiazolidine-2,4-dione (I) was studied spectrophotometrically at 25°. The kinetics of rapid ring cleavage to MeNCHOSCH2CO2– (II) was measured at pH 9.8-10.2 (carbonate buffers),whereas II decomposition to SCH2CO2– was followed in 0.005-0.02 M NaOH. The splitting of MeNHCOSCH2CO2Me (III) into HSCH2CO2Me and MeNHCO2Me is the rate-determining step in the MeO–-catalyzed methanolysis. The reverse cyclization of III was measured in methanolic BuNH2-BuNH3+ Cl– buffers (pKa 11.7). In the experiment, the researchers used many compounds, for example, 3-Methylthiazolidine-2,4-dione (cas: 16312-21-3Recommanded Product: 16312-21-3).
3-Methylthiazolidine-2,4-dione (cas: 16312-21-3) belongs to thiazolidine derivatives. Thiazolidines undergo hydrolysis to aldehyde and amino thiol under acid or basic aqueous conditions. Thiazolidine is prepared as it was in its first reported synthesis, by the condensation of cysteamine and formaldehyde. Other thiazolidines may be synthesized by similar condensations. A notable derivative is 4-carboxythiazolidine, derived from formaldehyde and cysteine.Recommanded Product: 16312-21-3
Referemce:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com