Functionalization of Meldrum’s acid by Diels-Alder approach was written by Kotha, Sambasivarao;Gaikwad, Vidyasagar. And the article was included in Heterocycles in 2022.Electric Literature of C4H5NO2S This article mentions the following:
Author’s have synthesized several Meldrum’s acid derivatives using Diels-Alder reaction as a key step. Here, the key sultine derivative is prepared by rongalite and the sultine derivative is useful as a latent diene. In the experiment, the researchers used many compounds, for example, 3-Methylthiazolidine-2,4-dione (cas: 16312-21-3Electric Literature of C4H5NO2S).
3-Methylthiazolidine-2,4-dione (cas: 16312-21-3) belongs to thiazolidine derivatives. Derivatives, thiazolidines, are known. For example, the drug pioglitazone contains a thiazolidine ring. Another drug that contains a thiazolidine ring is the antibiotic penicillin. Thiazolidine and its composites are key components of many natural products and drugs , and are also present in many synthetic compounds such as anticancer, anti-inflammatory, antitubercular, antifungal, antiviral, anti-HIV, cytotoxicity, antitrypanosomal, antinociceptive and anti-hypernociceptive compounds.Electric Literature of C4H5NO2S
Referemce:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com