A highly stereoselective reaction in aminolysis of 3-acyl-4(S)-isopropyl-1,3-thiazolidinethione with racemic amines was written by Jeong, Tae Myoung;Park, Ki Hun. And the article was included in Taehan Hwahakhoe Chi in 1988.COA of Formula: C6H11NS2 This article mentions the following:
Chiral recognition was observed in aminolysis of title thiazolidinethiones I [R = Me(CH2)10, 1-C10H7] by racemic amino acid esters to give an optically active amide (S-excess) and amino acid esters (R-excess). The rate of this aminolysis is affected by steric surrounding; completion of reaction can be easily judged by the disappearance of the original yellow color of I. I were synthesized from (S)-4-isopropyl-1,3-thiazolidine-2-thione and carboxylic acids. In the experiment, the researchers used many compounds, for example, (S)-4-Isopropylthiazolidine-2-thione (cas: 76186-04-4COA of Formula: C6H11NS2).
(S)-4-Isopropylthiazolidine-2-thione (cas: 76186-04-4) belongs to thiazolidine derivatives. Thiazolidine is a heterocyclic compound with five-membered saturated ring with a thioether group and an amine group in 1 and 3 positions of the ring. Open-chain compounds are obtained when thiazolidines are treated with tris(trimethylsilyl)silane in a reaction in which the thiazolidine derivatives act as a source of α-aminoalkyl radicals.COA of Formula: C6H11NS2
Referemce:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com