Introduction of a new synthetic route about 3-Aminorhodanine

1438-16-0, With the rapid development of chemical substances, we look forward to future research findings about 1438-16-0

3-Aminorhodanine, cas is 1438-16-0, it is a common heterocyclic compound, the thiazolidine compound, its synthesis route is as follows.

General procedure: A mixture of isothiocyanatobenzenesulfonamide 2 [32](0.01mol) and heterocyclic amine (0.01mol) in dioxane (30mL) containing triethylamine (0.1mL) was refluxed for 1h. The solvent was evaporated under reduced pressure and the solid obtained was filtered, washed with petroleum ether (bp 40-60C) and crystallized from ethanol to afford the thiourea derivatives.

1438-16-0, With the rapid development of chemical substances, we look forward to future research findings about 1438-16-0

Reference£º
Article; Ghorab, Mostafa M.; Alsaid, Mansour S.; El-Gaby, Mohamed S.A.; Safwat, Nesreen A.; Elaasser, Mahmoud M.; Soliman, Aiten M.; European Journal of Medicinal Chemistry; vol. 124; (2016); p. 299 – 310;,
Thiazolidine – Wikipedia
Thiazolidine – ScienceDirect.com