Introduction of a new synthetic route about 2682-49-7

2682-49-7, With the rapid development of chemical substances, we look forward to future research findings about 2682-49-7

Thiazolidin-2-one, cas is 2682-49-7, it is a common heterocyclic compound, the thiazolidine compound, its synthesis route is as follows.

(d) A mixture containing 3.09 g (0.03 mol) of 2-thiazolidinone, 11.2 g of potassium carbonate, 1.8 g of potassium hydrogen carbonate, 0.5 ml of water, 30 ml of methyl isobutyl ketone and 3.0 ml (0.033 mol) of benzyl bromide is refluxed for 7 hours. After cooling down, the reaction mixture is washed twice with 30 ml of water each, the organic phase is dried and evaporated. The yellow oily product (which solidifies on standing) may be purified by column chromatography (by using Kieselgel 60 of 230-400 mesh as sorbent and chloroform as eluent) to give 3.2 g (55.2%) of the title compound, m.p.: 50-51 C.

2682-49-7, With the rapid development of chemical substances, we look forward to future research findings about 2682-49-7

Reference£º
Patent; Richter Gedeon Vegyeszeti Gyar Rt.; US4937252; (1990); A;,
Thiazolidine – Wikipedia
Thiazolidine – ScienceDirect.com