Safety of Chalcone. I found the field of Chemistry very interesting. Saw the article A Chemometric Analysis of Compounds from Native New Zealand Medicinal Flora published in 2019.0, Reprint Addresses Reynisson, J (corresponding author), Univ Auckland, Sch Chem Sci, Private Bag 92019, Auckland 1142, New Zealand.. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone.
Several hundred (396) compounds from New Zealand flora with medicinal properties were analyzed for their physicochemical properties. It was found that approximately 10% fulfilled all the requirements to be considered to be lead-like, over half of the compounds were deemed to be in the drug-like space and approximate to 75% were in the known drug space. These results indicate the presence of a significant proportion of compounds that are of particular interest to pursue as potential lead compounds or therapeutics. Additionally, compound classes were analyzed separatelymost carbonyl-containing compounds (aldehydes, ketones, esters and lactones), along with phenols were the most lead-like compounds, which also displayed very good proportions in the drug-like and known drug space. The information presented herein can be harnessed and utilized in future work, through focussing on the compounds and compound classes that exhibit high-levels of lead-likeness for further development.
Safety of Chalcone. About Chalcone, If you have any questions, you can contact Pilkington, LI; Yang, X; Liu, MW; Hemar, Y; Brimble, MA; Reynisson, J or concate me.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com