So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Paine, John B. III; Dolphin, David researched the compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate( cas:2199-44-2 ).Reference of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate.They published the article 《5-Unsubstituted 2-pyrrolecarboxaldehydes for porphyrin synthesis and the cyanovinyl protecting group》 about this compound( cas:2199-44-2 ) in Journal of Organic Chemistry. Keywords: pyrrolecarboxaldehyde porphyrin intermediate preparation. We’ll tell you more about this compound (cas:2199-44-2).
(Cyanovinyl)pyrroles I (R = Me, R1 = Et, octyl; R = Et, R1 = Me) derived from the Knoevenagel condensation of benzyl 5-formyl-2-pyrrolecarboxylates with NCCH2CO2Me were employed in a facile sequence of 4 steps to produce, regioselectively, 2-pyrrolecarboxaldehydes II, important intermediates for porphyrin synthesis. Each step proceeded in 90-95% yield, making II available smoothly from benzyl 5-methyl-2-pyrrolecarboxylates in 7 steps, with an overall yield of 66-72%.
If you want to learn more about this compound(Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate)Reference of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(2199-44-2).
Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com