Flexible application of in synthetic route 1428537-19-2

In some applications, this compound(1428537-19-2)COA of Formula: C13H15F3N2O is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

COA of Formula: C13H15F3N2O. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: (R)-4-(tert-Butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole, is researched, Molecular C13H15F3N2O, CAS is 1428537-19-2, about Enantioselective N-Alkylation of Indoles via an Intermolecular Aza-Wacker-Type Reaction. Author is Allen, Jamie R.; Bahamonde, Ana; Furukawa, Yukino; Sigman, Matthew S..

In the presence of Pd(MeCN)2(OTs)2 and a nonracemic pyridinyloxazoline, 3-substituted indoles such as 3-phenylindole underwent intermol., chemoselective, and enantioselective alkylation/aza-Wacker reactions with cis-allylic and cis-homoallylic alcs. such as (Z)-EtCH:CHCH2OH mediated by p-benzoquinone in 1,2-dichloroethane to yield nonracemic β- and γ-(1-indolyl)alkanals such as I; enamines generated under other conditions were not formed. The mechanism was studied using the reaction of a deuterium-labeled allylic alc.; the stereochem. of the product supported a syn amino-palladation mechanism for the reaction.

In some applications, this compound(1428537-19-2)COA of Formula: C13H15F3N2O is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com