Application In Synthesis of Chalcone. Recently I am researching about ONE-POT SYNTHESIS; FACILE SYNTHESIS; 3-COMPONENT REACTIONS; 4-COMPONENT REACTIONS; EXPEDIENT SYNTHESIS; EFFICIENT SYNTHESIS; CATALYST; HYDROGENATION; PROTOCOL; CASCADE, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [2171101076, 21872060]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Chen, SM; Ravichandiran, P; El-Harairy, A; Queneau, Y; Li, MH; Gu, YL. The CAS is 94-41-7. Through research, I have a further understanding and discovery of Chalcone
A straightforward access to tricyclic indoles bearing 3,4-fused seven-membered rings has been established by using 4-aminoindoles as 1,4-bisnucleophiles in three-component reactions. 1H-Azepino[4,3,2-cd]indoles, 4,6-dihydro-1H-azepino[4,3,2-cd]indoles and 1,3,4,6-tetrahydro-5H-azepino[4,3,2-cd]indol-5-ones could thus be synthesized in one pot in moderate to good yields. Beyond opening access to 3,4-fused tricyclic indoles, the use of easily accessible 4-aminoindoles as C,N-1,4-bisnucleophiles also provides a new platform to be used in a diversity-oriented synthesis strategy, fully displaying its benefits of maximizing molecular complexity and reaction diversity.
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Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com