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Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof
The invention relates to nitrogen- and sulfur–containing heterocyclic compounds of the formula (I), wherein, Ar represents an optionally mono- or polysubstituted aryl or heteroaryl group;, R1 represents a carbonyl or (C2 6alkenyl)–carbonyl group;, R2 represents a hydrogen atom, or a C1 6alkyl, phenyl or phenyl(C1 4alkyl) group;, R3 represents a hydrogen atom or a (C1 6 alkoxy)carbonyl group;, R4 and R5, which may be the same or different, represent a hydrogen atom or a C1 6alkyl group;, R6 represents a hydrogen atom or a C1 6alkyl group or halophenyl group;, m is 0 or 1; and, n is 1 or 2,with the proviso that R2 is a hydrogen atom when m is 0, and acid addition salts of the compounds of formula (I) and pharmaceutical compositions thereof. The invention also relates to processes for the preparation of these compounds. The compounds of formula (I) show a significant cerebral antihypoxic activity.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Product Details of 2682-49-7, you can also check out more blogs about2682-49-7
Reference£º
Quinuclidine – Wikipedia,
Quinuclidine | C7H192N | ChemSpider