Final Thoughts on Chemistry for 1428537-19-2

Here is a brief introduction to this compound(1428537-19-2)Category: thiazolidine, if you want to know about other compounds related to this compound(1428537-19-2), you can read my other articles.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Quaternary stereocentres via catalytic enantioconvergent nucleophilic substitution reactions of tertiary alkyl halides, published in 2021-03-31, which mentions a compound: 1428537-19-2, Name is (R)-4-(tert-Butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole, Molecular C13H15F3N2O, Category: thiazolidine.

The development of efficient methods, particularly catalytic and enantioselective processes, for the construction of all-carbon quaternary stereocentres is an important (and difficult) challenge in organic synthesis due to the occurrence of this motif in a range of bioactive mols. One conceptually straightforward and potentially versatile approach is the catalytic enantioconvergent substitution reaction of a readily available racemic tertiary alkyl electrophile by an organometallic nucleophile; however, examples of such processes are rare. Here we demonstrate that a nickel-based chiral catalyst achieves enantioconvergent couplings of a variety of tertiary electrophiles (cyclic and acyclic α-halocarbonyl compounds) with alkenylmetal nucleophiles to form quaternary stereocentres with good yield and enantioselectivity under mild conditions in the presence of a range of functional groups. These couplings, which probably proceed via a radical pathway, provide access to an array of useful families of organic compounds, including intermediates in the total synthesis of two natural products, (-)-eburnamonine and madindoline A.

Here is a brief introduction to this compound(1428537-19-2)Category: thiazolidine, if you want to know about other compounds related to this compound(1428537-19-2), you can read my other articles.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com