Reference of 7025-19-6, In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, Reference of 7025-19-6, name is 3-(4-Oxo-2-thioxothiazolidin-3-yl)propanoic acid, introducing its new discovery.
A benzimidazole derivative, its preparation method and in anti-tumor applications (by machine translation)
The present invention provides a kind of benzimidazole derivatives, have the formula (I) has a structure shown in; wherein R1 And R2 Independently selected from hydrogen, halogen, alkyl, alkoxy, halogenated alkyl, nitro and nitrile in the a; R3 For carboxyl, alkyl, phenyl or cyano; m of the value range is 0 – 3; n of the value range is 0 – 3; X is CH or nitrogen; Y is CH2 Or carbonyl. The invention discloses a benzimidazole derivative to a topoisomerase II activity of very strong restraining effect, therefore, can be used as a topoisomerase II inhibitor. The study found that, said compound of the invention is Topo II catalytic inhibitors. Therefore, can be used for preparing topoisomerase II as the target of the anti-tumor drug. At the same time, said styrene and imidazole derivatives to the multi-tumor cells has good […] activity, so this invention the benzimidazole derivatives can be used for the preparation of anti-cancer drug. (by machine translation)
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Quinuclidine – Wikipedia,
Quinuclidine | C7H793N | ChemSpider