Synthetic Route of 6118-51-0, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 6118-51-0, Name is exo-3,6-Epoxy-1,2,3,6-tetrahydrophthalic Anhydride, SMILES is O=C1OC([C@@]2([H])[C@](O3)([H])C=C[C@]3([H])[C@]21[H])=O, belongs to thiazolidines compound. In a article, author is Marc, Gabriel, introduce new discover of the category.
MICROWAVE ASSISTED SYNTHESIS OF 3,5-DISUBSTITUTED THIAZOLIDINE-2,4-DIONES WITH ANTIFUNGAL ACTIVITY. DESIGN, SYNTHESIS, VIRTUAL AND IN VITRO ANTIFUNGAL SCREENING
Twelve thiazolidin-2,4-diones were obtained by microwave assisted synthesis. All the synthesized compounds were physicochemically characterized and the IR (infrared spectra), H-1-NMR (proton nuclear magnetic resonance) and MS (mass spectrometry) data were consistent with the assigned structures. All the compounds were tested for their in vitro antifungal properties against several strains of Candida and all compounds exhibited efficient anti-Candida activity. Molecular docking studies were performed to investigate the mode of action towards the fungal lanosterol 14 alpha-demethylase. The results of the in vitro antifungal activity screening and docking study revealed that the synthesized compounds are potential anti-Candida agents that might act by inhibiting the fungal lanosterol 14 alpha-demethylase and can be further optimized and developed as lead compounds.
Synthetic Route of 6118-51-0, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 6118-51-0.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com