Chemistry can be defined as the study of matter and the changes it undergoes. category: thiazolidine. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.category: thiazolidine, Name is Thiazolidin-2-one, molecular formula is C3H5NOS, introducing its new discovery.
Recent advances in the discovery of small molecules targeting glioblastoma
Glioblastoma (GBM) is one of the most common central nervous system cancers. It is characterized as a fast-growing tumor that arises from multiple cell types with neural stem-cell-like properties. Additionally, GBM tumors are highly invasive, which is attributed to the presence of glioblastoma stem cells that makes surgery ineffective in most cases. Currently, temozolomide is the unique chemotherapy option approved by the U.S. Food and Drug Administration for GBM treatment. This review analyzes the emergence and development of new synthetic small molecules discovered as promising anti-glioblastoma agents. A number of compounds were described herein and grouped according to the main chemical class used in the drug discovery process. Importantly, we focused only on synthetic compounds published in the last 10 years, thus excluding natural products. Furthermore, we included in this review only those most biologically active compounds with proven in vitro and/or in vivo efficacy.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.category: thiazolidine, you can also check out more blogs about2682-49-7
Reference£º
Quinuclidine – Wikipedia,
Quinuclidine | C7H282N | ChemSpider