Category: 2199-44-2

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Some reactions of 2,4-dimethylmagnesylpyrrole》. Authors are Ingraffia, F..The article about the compound:Ethyl 3,5-Dimethyl-2-pyrrolecarboxylatecas:2199-44-2,SMILESS:O=C(C1=C(C)C=C(C)N1)OCC).Safety of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. Through the article, more information about this compound (cas:2199-44-2) is conveyed.

Because of the anomalous behavior of magnesylpyrrole with SOCl2 (I) and CS2 (cf. Oddo and Mingoia, C. A. 21, 1458), it was decided to study their action as well as that of ClCO2Et (II) on a little studied derivative of pyrrole, viz., 2,4-dimethylpyrrole (III) in the form of its magnesyl derivative (IV), and on magnesylpyrroles with neg. radicals (to stabilize the ring). IV and II in anhydrous Et2O, heated, and decomposed with ice, yield Et 2,4-dimethyl-5-pyrrolecarboxylate, HN.CMe:CH.CMe:CCO2Et (V), slightly yellow, m. 124°. I in Et2O added to ice-cold IV (2 mols.) in Et2O, after standing decomposed with ice, neutralized with NaHCO3 and purified with difficulty (Et2O, petr. ether, Me2CO and C6H6), yields 3,5,3′,5′-tetramethylpyrro-(2,2′)-sulfone, (HN.CMe:CH.CMe:C)2SO2, dark violet, decomposes around 95° stable toward hot alk. hydroxides, is not reduced by Zn and AcOH, is decomposed with evolution of H2S by Sn in hot HCl. Ag derivative, probably an α’-derivative IV and CS2 in Et2O heated, decomposed with ice, acidified with H2O4, the Et2O-soluble product treated with aqueous NaOH, and acidified when ice-cold, precipitates 2,4-dimethyl-5-dithiopyrrolecarboxylic acid, HN.CMe:CH.CMe:CC(:S)SH (VI), also obtained directly but very impure by drying the Et2O-soluble portion (loc. cit.). It is unstable and immediately oxidizes to 2,4-dimethylthiopyrrole disulfide, [HN.CMe:CH.CMe:CC(:S)S-]2, red, m. 156°. With neutral Pb(OAc)2, the aqueous Na salt (VII) of VI precipitates the Pb salt, [HN.CMe:CH.CMe:CC(:S)S]2Pb, yellow. In darkness, aqueous VI and AgNO3 precipitate the Ag salt, HN.CMe:CH.CMe:CC(:S)SAg, brick-red. No Zn salt is precipitated from aqueous VII and Zn(OAc)2. It was then to be determined whether with a compound containing a neg. CO2Et group, e. g., V, the reaction with EtMgBr is normal, and if so to determine the behavior of the new metal derivative in comparison with III. Actually V and EtMgBr in anhydrous Et2O evolve C2H6 and form the magnesyl derivative (VIII), BrMgN.CMe:CH.CMe:CCO2Et or HN.CMe:C(MgBr).CMe:CCO2Et, yellowish oil. Heated with CS2 or with AcCl in anhydrous Et2O, VIII remains unaltered. This incapacity to react probably depends upon the assumption of the enolic form, N:CMe.CH:CMe.C:C(OMgBr)OEt, as was found with alkyl pyrryl ketones by Oddo (C. A. 19, 2492; Gazz. chim. ital. 40, ii, 15(1910); cf. C. A. 4, 2460).

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Abraham, Raymond J.; Lapper, Roy D.; Smith, Kevin M.; Unsworth, John F. published an article about the compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate( cas:2199-44-2,SMILESS:O=C(C1=C(C)C=C(C)N1)OCC ).Product Details of 2199-44-2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:2199-44-2) through the article.

The 13C NMR spectra of 55 pyrroles were determined and assigned. The pyrrole ring carbon chem. shifts were predicted, to ∼0.5 ppm, on the basis of additive substituent effects and contributions from steric and conjugative effects. The substituent chem. shift parameters were analogous to those for thiophenes. C-2 substituents affected mainly C-3 and C-5, and C-3 substituents mainly C-2.

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In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Studies on the synthesis of porphyrin a. II. Synthesis of porphyrins with higher saturated and unsaturated acyl substituents, published in 1976, which mentions a compound: 2199-44-2, Name is Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, Molecular C9H13NO2, Electric Literature of C9H13NO2.

Deuteroporphyrins IX [I, R1 = Me2C:CH(CH2)2CMe:CH(CH2)2CMe:CHCH2, Me2CH(CH2)3CHMe(CH2)3CHMe(CH2)2, Me2CBrCHBr(CH2)2CBrMeCHBr(CH2)2CBrMeCHBrCH2] were obtained in 33-92% yields by cyclization of the corresponding biladienes II, prepared from a pyrrole derivative and a tripyrrene.

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The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Perylene and its derivatives. XLIX. The perylene trihalides of K. Brass and E. Clar》. Authors are Zinke, A.; Pongratz, A.; Scholtis, K.; Hanus, F..The article about the compound:Ethyl 3,5-Dimethyl-2-pyrrolecarboxylatecas:2199-44-2,SMILESS:O=C(C1=C(C)C=C(C)N1)OCC).Name: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. Through the article, more information about this compound (cas:2199-44-2) is conveyed.

cf. C. A. 30, 6362.7. It had been shown that Brass and Clar’s “”perylene tribromide”” (C. A. 27, 720) is not a substance of constant composition and that the primary product of the action of Br on perylene is rather a tetrabromide. In a reply, B. and C. (C. A. 30, 6735.3) lay stress on the constancy in composition of their tribromide and deplore the fact that Z. and P. give the results of only 1 of the numerous analyses of their Br product. To meet this criticism a number of further bomb determinations are reported, although the authors believe their earlier data suffice to establish their contention. B. and C. also doubt the constancy of the composition of the tetrabromide and believe the higher Br values obtained by Z. and P. are due to the fact that they did not remove the excess of Br at an elevated temperature Some determinations are now reported in which the excess Br was removed with a current of warm (50-60°) air; they, too, show distinctly that 4 atoms Br are first taken up. Repeated treatment of the product with warm air showed that the loss in weight is at first due almost exclusively to evaporation of the mechanically attached Br, and when this ceases to be given off the compound has the composition of a tetrabromide. Further loss of Br as HBr occurs at an appreciably slower rate; a preparation kept in a desiccator for hrs. still contained considerably more Br than the amount calculated for a tribromide. The substance prepared by the action of I on perylene in hot benzene according to the (very incomplete) directions of B. and C. likewise has not a constant composition and was always found to contain more I than that calculated for a triiodide; the I content of the beautifully crystalline product depended on the concentration and the total amount of I dissolved in the benzene.

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Safety of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, is researched, Molecular C9H13NO2, CAS is 2199-44-2, about Synthesis and some reactions of pyrroles with aliphatic acyl substituents. Author is Mironov, A. F.; Ol’shanskaya, N. B.; Zhestkov, V. P.; Evstigneeva, R. P..

4-Acylpyrrolecarboxylates (I; R = EtCO, C15H31CO, C17H35CO) were prepared in about quant. yields of Friedel-Crafts acylation of I (R = H). Reduction of I by NaBH4 gave 82-97% of alc. (II; R = Et, C15H31, R1 = H). Heating II (R = C15H31, R1 = H) in pyridine with Ac2O gave 96% acryl derivative II (R = C15H31, R1 = Ac). Treatment of I (R = C17H35CO) with Pb(OAc)4 gave an acylated intermediate which with 40% HBr and MeOH gave 85% pyrrole (III; R = C17H35CO, R1 = MeO). Similarly III (R = C15H31CO, R1 = Cl) was obtained in 75% yield.

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Yu, Xiang-hao; Yang, Nian-fa; Cao, Jing published an article about the compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate( cas:2199-44-2,SMILESS:O=C(C1=C(C)C=C(C)N1)OCC ).Safety of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:2199-44-2) through the article.

The synthesis of 2-(ethoxycarbonyl)-3,4-dimethylpyrrole (I) was studied. A series of substituted 2-(ethoxycarbonyl)pyrrole was prepared by reaction of oxo olefin salt with di-Et aminomalonate. For example, refluxing MeCOCMe:CHONa with di-Et aminomalonate in aqueous HOAc for 2 h gave 35% I.

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In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called The special features of the thermal oxidative destruction of isomeric dipyrrolylmethanes, published in 2006, which mentions a compound: 2199-44-2, Name is Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, Molecular C9H13NO2, SDS of cas: 2199-44-2.

3,3′,4,4′-Tetramethyl-5,5′-dicarbethoxydipyrrolylmethane-2,2′ and its α,β and β,β isomers were synthesized. The compounds were characterized by recording their proton NMR spectra. The thermal oxidative destruction of the compounds was studied thermogravimetrically. The results were used to determine the temperature and enthalpy characteristics of fusion and the temperatures of the beginning and maxima of the exothermic effects of the destruction of dipyrrolylmethanes in air oxygen. The thermal stability of dipyrrolylmethanes was found to be primarily determined by mol. isomerism and increase for sym. substituted α,α- and β,β-dipyrrolymethanes compared with the α,β isomer.

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Synthetic Route of C9H13NO2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, is researched, Molecular C9H13NO2, CAS is 2199-44-2, about Molecular Rectangle Formed by Head-to-tail Self-Assembly of 1-(Dipyrrin-2-yl)-1′-(dipyrrin-3-yl)methane. Author is Yang, Lanying; Zhang, Yi; Chen, Qingqi; Ma, Jin Shi.

1-(Dipyrrin-2-yl)-1′-(dipyrrin-3-yl)methane (I), the N-confused analog of biladiene-ac, was prepared by condensation of 2,3′-dipyrromethane with two mols. of 2-formylpyrrole in CH2Cl2 in the presence of HBr. Self-assembly of the ligand with Zn(II) in CH2Cl2 and MeOH offers a dinuclear dimeric complex with a ligand:metal ratio of 2:2. X-ray crystal structure anal. reveals two ligands bound through a head-to-tail pattern to two Zn centers to form a severely distorted helical conformation, which has the shape of a rectangle.

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So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Khan, Shafiq A.; Plieninger, Hans researched the compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate( cas:2199-44-2 ).Application In Synthesis of Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate.They published the article 《Synthesis of a tripyrrin-14-carboxylic acid with two neopentyl groups》 about this compound( cas:2199-44-2 ) in Chemische Berichte. Keywords: tripyrrincarboxylic acid; metal complex tripyrrincarboxylic acid. We’ll tell you more about this compound (cas:2199-44-2).

Tripyrrincarboxylic acid I was prepared from pyrrole II by condensation with Me3CCHO and HI to give iodo derivative III which was reduced to IV. SO2Cl2 reacted with IV to give V, which was hydrolyzed to aldehydic acid VI. This condensed with 3,4-dimethyl-3-pyrrolin-2-one to pyrromethenone VII, which was decarboxylated to VIII. VI condensed with VIII to give I. Metal complexes of I are soluble in most organic solvents even after crystallization

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Synthetic Route of C9H13NO2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: Ethyl 3,5-Dimethyl-2-pyrrolecarboxylate, is researched, Molecular C9H13NO2, CAS is 2199-44-2, about New method for synthesis of (ω-chloroalkyl)pyrroles. Author is Tu, Bin; Wang, Changqi; Ma, Jinshi.

Et 4-(ω-chloroalkyl)-3,5-dimethyl-1H-pyrrole-2-carboxylates (alkyl = Et, Pr, butyl) were prepared in >96% yields from Et 4-(ω-chloroacyl)-3,5-dimethyl-1H-pyrrole-2-carboxylates by treatment with NaBH4 followed by BF3·Et2O in THF. The ω-chloroacyl derivatives were prepared from 2-(ethoxycarbonyl)-3,5-dimethylpyrrole (1) by Friedel-Crafts reaction in >91% yields. 1 Was prepared in one step from 2,4-pentanedione and di-Et aminomalonate or di-Et oximinomalonate according to literature methods.

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