A common heterocyclic compound, the thiazolidine compound, name is (S)-4-Phenylthiazolidine-2-thione,cas is 185137-29-5, mainly used in chemical industry, its synthesis route is as follows.
The compound of formula (XI) (4.8 g, 25 mmol) was added to a 250 mL round bottom flask at 0 C.Azidoacetic acid (3g,30mmol),Dicyclohexylcarbodiimide (5.7 g, 27 mmol),4-dimethylaminopyridine (370 mg, 3.0 mmol),Dichloromethane100mL, after 30min, rise to room temperature,After 1 h of reaction, the silica gel was filtered.Wash with cyclohexane: ethyl acetate = 7:3,Concentrated crude liquid,Then, it was recrystallized from dichloromethane/petroleum ether to give the product 6.5 g, yield 94.2%.
185137-29-5, As the rapid development of chemical substances, we look forward to future research findings about 185137-29-5
Reference£º
Patent; Chinese Academy Of Medical Sciences Pharmaceutical Institute; Xie Ping; Liu Xiaoyu; Jiao Xiaozhen; Li Xiaoyu; Yang Hongguang; Shi Xiang; Yang Feilong; (17 pag.)CN108822072; (2018); A;,
Thiazolidine – Wikipedia
Thiazolidine – ScienceDirect.com