Category: 15965-55-6

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 15965-55-6, is researched, Molecular C7H4ClN3O2, about Synthesis and biological activity of 5,6-dinitro derivatives of benzimidazole, the main research direction is virucide dinitrobenzimidazole; benzimidazole dinitro virucide bactericide; bactericide dinitrobenzimidazole.Synthetic Route of C7H4ClN3O2.

The title compounds I [R = H·HCl, Me; R1 = NH2NH, amino, azolyl (II)] were prepared from chlorobenzimidazoles I [R1 = Cl (III)]. III in turn, were prepared by the nitration of 2-chlorobenzimidazole. The antiviral and antimicrobial activity of II were examined

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Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 15965-55-6, is researched, Molecular C7H4ClN3O2, about Heterocyclic betaines. XXII. Azinium(azolium) 4-nitrobenzimidazolate inner salts and their derivatives with several interannular spacers. Synthesis, characterization and antitrichomonal activity, the main research direction is nitrobenzimidazolate pyridinium imidazolium preparation antiprotozoal activity.Recommanded Product: 15965-55-6.

The synthesis of an ensemble of pyridinium(imidazolium) 4-nitrobenzimidazolate betaines and their derivatives with several interannular linkages has been explored. Their antiprotozoal activity has also been examined

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Thiazolidine – Wikipedia,
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So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Alcalde, Ermitas; Perez-Garcia, Lluiesa; Dinares, Immaculada; Frigola, Jordi researched the compound: 2-Chloro-7-nitro-1H-benzo[d]imidazole( cas:15965-55-6 ).Recommanded Product: 15965-55-6.They published the article 《Heterocyclic betaines. XXII. Azinium(azolium) 4-nitrobenzimidazolate inner salts and their derivatives with several interannular spacers. Synthesis, characterization and antitrichomonal activity》 about this compound( cas:15965-55-6 ) in Chemical & Pharmaceutical Bulletin. Keywords: nitrobenzimidazolate pyridinium imidazolium preparation antiprotozoal activity. We’ll tell you more about this compound (cas:15965-55-6).

The synthesis of an ensemble of pyridinium(imidazolium) 4-nitrobenzimidazolate betaines and their derivatives with several interannular linkages has been explored. Their antiprotozoal activity has also been examined

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Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Acid dissociation constants of some benzo-substituted 2-chlorobenzimidazoles, published in 1966, which mentions a compound: 15965-55-6, mainly applied to BENZIMIDAZOLES DISSOCN; DISSOCN BENZIMIDAZOLES; CHLOROBENZIMIDAZOLES DISSOCN, Safety of 2-Chloro-7-nitro-1H-benzo[d]imidazole.

The measurements of the apparent pK were measured in water with 2% MeOH at a constant ionic strength of 0.5 from derivatives by substitution in the 5(6) and 4(7) positions. The following values were obtained: H, 9.3; 5(6) Me, 9.5; 5(6) Cl, 8.5; 5(6) NO2, 7.4; 4(7) Me, 9.6; 4(7) Cl 8.4; 4(7) NO2 7.5. The acidity justifies the hypothesis that in the presence of methoxy ions the compounds are transformed in the conjugate bases and without nucleophilic reactivity. With piperidine and PhSH the nucleophilic reaction is possible.

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Reference:
Thiazolidine – Wikipedia,
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In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthesis and antitrichomonal activity of azinium (azolium) 4-nitrobenzimidazolate betaines and their derivatives, published in 1992-03-31, which mentions a compound: 15965-55-6, mainly applied to protozoacide nitrobenzimidazolate betaine; trichomonacide nitrobenzimidazolate betaine; benzimidazolate nitro betaine trichomonacide, Electric Literature of C7H4ClN3O2.

Among the many attractive types of heterocyclic betaines, the inner salts of azinium azolates and azolium azolates are few and scattered. The antiprotozoal activity (in vitro) against Trichomonas vaginalis of a variety of mesomeric betaines of pyridinium azolates, their N-azolylpyridinium salts, and N-5-nitrobenzimidazol-2-ylpyridinium derivatives, e.g. 1-(5-nitro-1H-benzimidazol-2-yl)-2,4,6-triphenylpyridinium salts was reported. In the present study, 1-(4-nitro-1H-benzimidazol-2-yl)pyridinium salts were prepared and tested against T. vaginalis in vitro and in vivo.

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Reference:
Thiazolidine – Wikipedia,
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SDS of cas: 15965-55-6. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 2-Chloro-7-nitro-1H-benzo[d]imidazole, is researched, Molecular C7H4ClN3O2, CAS is 15965-55-6, about Benzimidazoles. II. Effect of benzene nucleus substituents on the nuclopphilic reactivity of some 2-chloro-benzimidazoles.

cf. CA 67: 64300p. An equimol. mixture of 4,2-R(H2N)C6H3NH2.2HCl, or 3,2-R(H2N)C6H3NH2.2HCl and urea, heated 20 min. at 160-80°, the reaction mixture extracted with hot 10% NaOH and the alk. solution acidified with HCl, precipitated known 5(6)-substituted- or 4(7)-substituted-2-benzimidazolones, resp., which (0.01 mole) with 0.07 mole POCl3 and a few drops of concentrated HCl, heated 3-4 hrs. at 160-70° in a sealed tube yielded the following I (R, m.p., and % yield given): 5(6)-NO2, 222-3°, -; 5(6)-Cl, 207-8°, 70; 5(6)-Me, 185-6°, 72; 5(6)-MeO, 170-1°, 40; 4(7)-NO2, 196-7°, 40; 4(7)-Cl, 187-8°, 70; 4(7)-Me, 141-2°, 50; 4(7)-MeO, 151-2°, 55. Kinetic studies on the nucleophilic reactivity of I, carried out with piperidine at 100°, indicated that the 2-Cl mobility increases when R is electron-withdrawing, and decreases when R is electron donor. A linear correlation was also found for the effect of the substituents on the reaction center with σmeta + σpara for the position 5(6) and σortho + σmeta for the 4(7)-position, resp.

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Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Electric Literature of C7H4ClN3O2. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 2-Chloro-7-nitro-1H-benzo[d]imidazole, is researched, Molecular C7H4ClN3O2, CAS is 15965-55-6, about Benzimidazoles. II. Effect of benzene nucleus substituents on the nuclopphilic reactivity of some 2-chloro-benzimidazoles. Author is Ricci, Alfredo; Vivarelli, Piero.

cf. CA 67: 64300p. An equimol. mixture of 4,2-R(H2N)C6H3NH2.2HCl, or 3,2-R(H2N)C6H3NH2.2HCl and urea, heated 20 min. at 160-80°, the reaction mixture extracted with hot 10% NaOH and the alk. solution acidified with HCl, precipitated known 5(6)-substituted- or 4(7)-substituted-2-benzimidazolones, resp., which (0.01 mole) with 0.07 mole POCl3 and a few drops of concentrated HCl, heated 3-4 hrs. at 160-70° in a sealed tube yielded the following I (R, m.p., and % yield given): 5(6)-NO2, 222-3°, -; 5(6)-Cl, 207-8°, 70; 5(6)-Me, 185-6°, 72; 5(6)-MeO, 170-1°, 40; 4(7)-NO2, 196-7°, 40; 4(7)-Cl, 187-8°, 70; 4(7)-Me, 141-2°, 50; 4(7)-MeO, 151-2°, 55. Kinetic studies on the nucleophilic reactivity of I, carried out with piperidine at 100°, indicated that the 2-Cl mobility increases when R is electron-withdrawing, and decreases when R is electron donor. A linear correlation was also found for the effect of the substituents on the reaction center with σmeta + σpara for the position 5(6) and σortho + σmeta for the 4(7)-position, resp.

In some applications, this compound(15965-55-6)Electric Literature of C7H4ClN3O2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

Ricci, Alfredo; Vivarelli, Piero published an article about the compound: 2-Chloro-7-nitro-1H-benzo[d]imidazole( cas:15965-55-6,SMILESS:O=[N+](C1=C2NC(Cl)=NC2=CC=C1)[O-] ).Synthetic Route of C7H4ClN3O2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:15965-55-6) through the article.

The measurements of the apparent pK were measured in water with 2% MeOH at a constant ionic strength of 0.5 from derivatives by substitution in the 5(6) and 4(7) positions. The following values were obtained: H, 9.3; 5(6) Me, 9.5; 5(6) Cl, 8.5; 5(6) NO2, 7.4; 4(7) Me, 9.6; 4(7) Cl 8.4; 4(7) NO2 7.5. The acidity justifies the hypothesis that in the presence of methoxy ions the compounds are transformed in the conjugate bases and without nucleophilic reactivity. With piperidine and PhSH the nucleophilic reaction is possible.

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Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Chloro-7-nitro-1H-benzo[d]imidazole( cas:15965-55-6 ) is researched.Category: thiazolidine.Vivarelli, Piero; Taddei, Ferdinando published the article 《Benzimidazoles. Prototropic equilibriums and product distribution from methylation of substituted 2-chlorobenzimidazoles》 about this compound( cas:15965-55-6 ) in Gazzetta Chimica Italiana. Keywords: benzimidazole chloro methylation; methylation chlorobenzimidazole; tautomerization chlorobenzimidazole. Let’s learn more about this compound (cas:15965-55-6).

Methylation of the benzimidazoles I (R = Me, MeO, Cl, NO2, R1 = H) gave equal amounts of II and III. Methylation of I (R = H, R1 = Me, MeO, Cl, NO2) gave II and a larger amount of III. The ratio of tautomers was determined by NMR.

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Thiazolidine – Wikipedia,
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Computed Properties of C7H4ClN3O2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 2-Chloro-7-nitro-1H-benzo[d]imidazole, is researched, Molecular C7H4ClN3O2, CAS is 15965-55-6, about Heterocyclic betaines. XXII. Azinium(azolium) 4-nitrobenzimidazolate inner salts and their derivatives with several interannular spacers. Synthesis, characterization and antitrichomonal activity. Author is Alcalde, Ermitas; Perez-Garcia, Lluiesa; Dinares, Immaculada; Frigola, Jordi.

The synthesis of an ensemble of pyridinium(imidazolium) 4-nitrobenzimidazolate betaines and their derivatives with several interannular linkages has been explored. Their antiprotozoal activity has also been examined

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Reference:
Thiazolidine – Wikipedia,
Thiazolidine – ScienceDirect.com