Electric Literature of 108-59-8, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 108-59-8, Name is Dimethylmalonate, SMILES is O=C(OC)CC(OC)=O, belongs to thiazolidines compound. In a article, author is Jaiswal, Vandana, introduce new discover of the category.
[3+2]-Annulation of Azaoxyallyl Cations and Thiocarbonyls for the Assembly of Thiazolidin-4-ones
A base-promoted, efficient [3 + 2] annulation between azaoxyallyl cations and thiocarbonyls is reported for flexible access to highly functionalized thiazolidin-4-one derivatives in good to excellent yields. An intriguing feature of this method is the metal or Lewis acid free late-stage entry of distinct set of functional groups at C2 of thiazolidin-4-ones via substitution of a latent amino functional group. Overall, this approach constitutes a general platform for convenient access to this medicinally important scaffold.
Electric Literature of 108-59-8, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 108-59-8.
Reference:
Thiazolidine – Wikipedia,
,Thiazolidine – ScienceDirect.com