Awesome Chemistry Experiments For Thiazolidin-2-one

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One-pot synthesis of 4-thiazolidinone derivatives catalyzed by zinc acetate-schiff base complex immobilized on mesoporous molecular sieve MCM-41

A new simple and efficient one-pot synthesis of thiazolidinone derivatives via aldehydes, amines and mercaptoacetic acid in the presence of Zn(OAc)2-Schiff base complex immobilized on MCM-41 is described. A variety of aldehydes and amines were engaged in the study and afforded respective thiazolidinones in high yield (up to 98%). Moreover, consistent activity of recovered catalyst was found to be almost same up to five cycles in 80% yield.

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Quinuclidine – Wikipedia,
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